diff --git a/e2e-playwright/panels-suite/timeseries.spec.ts b/e2e-playwright/panels-suite/timeseries.spec.ts
new file mode 100644
index 00000000000..fb2124f7dda
--- /dev/null
+++ b/e2e-playwright/panels-suite/timeseries.spec.ts
@@ -0,0 +1,119 @@
+import { test, expect } from '@grafana/plugin-e2e';
+
+const DASHBOARD_UID = '1KxMUdE7k';
+
+test.use({
+  featureToggles: {
+    timeRangePan: true,
+  },
+});
+
+test.describe('Panels test: TimeSeries X-axis panning', { tag: ['@panels', '@timeseries'] }, () => {
+  test('cursor changes to grab hand over x-axis', async ({ gotoDashboardPage, page }) => {
+    await test.step('Load dashboard and verify cursor changes to grab', async () => {
+      const dashboardPage = await gotoDashboardPage({ uid: DASHBOARD_UID });
+
+      const timeseriesPanel = page.locator('.uplot').first();
+      await expect(timeseriesPanel, 'panel rendered').toBeVisible();
+
+      const xAxis = timeseriesPanel.locator('.u-axis').first();
+      await expect(xAxis, 'x-axis rendered').toBeVisible();
+
+      await xAxis.hover();
+
+      const cursorStyle = await xAxis.evaluate((el: HTMLElement) => window.getComputedStyle(el).cursor);
+      expect(cursorStyle, 'cursor is grab').toBe('grab');
+    });
+  });
+
+  test('drag right pans backward in time, drag left pans forward', async ({ gotoDashboardPage, page, selectors }) => {
+    let centerX: number;
+    let centerY: number;
+    let initialFromTime: number;
+    let initialToTime: number;
+
+    const dashboardPage = await test.step('Load dashboard and capture initial time range', async () => {
+      const dashboardPage = await gotoDashboardPage({ uid: DASHBOARD_UID });
+
+      const timeseriesPanel = page.locator('.uplot').first();
+      await expect(timeseriesPanel, 'panel rendered').toBeVisible();
+
+      const xAxis = timeseriesPanel.locator('.u-axis').first();
+      await expect(xAxis, 'x-axis rendered').toBeVisible();
+
+      const timePickerButton = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.openButton);
+      await timePickerButton.click();
+
+      const fromField = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.fromField);
+      const toField = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.toField);
+
+      const initialFrom = await fromField.inputValue();
+      const initialTo = await toField.inputValue();
+      initialFromTime = new Date(initialFrom).getTime();
+      initialToTime = new Date(initialTo).getTime();
+
+      await page.keyboard.press('Escape');
+
+      const axisBox = await xAxis.boundingBox();
+      if (!axisBox) {
+        throw new Error('X-axis bounding box not found');
+      }
+
+      centerX = axisBox.x + axisBox.width / 2;
+      centerY = axisBox.y + axisBox.height / 2;
+
+      return dashboardPage;
+    });
+
+    await test.step('Drag right pans backward in time', async () => {
+      await page.mouse.move(centerX, centerY);
+      await page.mouse.down();
+      await page.mouse.move(centerX + 100, centerY);
+      await page.mouse.up();
+
+      await page.waitForTimeout(1000);
+
+      const timePickerButton = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.openButton);
+      await timePickerButton.click();
+
+      const fromField = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.fromField);
+      const toField = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.toField);
+
+      const afterRightFrom = await fromField.inputValue();
+      const afterRightTo = await toField.inputValue();
+      const afterRightFromTime = new Date(afterRightFrom).getTime();
+      const afterRightToTime = new Date(afterRightTo).getTime();
+
+      expect(afterRightFromTime, 'panned backward').toBeLessThan(initialFromTime);
+      expect(afterRightToTime, 'panned backward').toBeLessThan(initialToTime);
+
+      await page.keyboard.press('Escape');
+
+      initialFromTime = afterRightFromTime;
+      initialToTime = afterRightToTime;
+    });
+
+    await test.step('Drag left pans forward in time', async () => {
+      await page.mouse.move(centerX, centerY);
+      await page.mouse.down();
+      await page.mouse.move(centerX - 100, centerY);
+      await page.mouse.up();
+
+      await page.waitForTimeout(1000);
+
+      const timePickerButton = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.openButton);
+      await timePickerButton.click();
+
+      const fromField = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.fromField);
+      const toField = dashboardPage.getByGrafanaSelector(selectors.components.TimePicker.toField);
+
+      const afterLeftFrom = await fromField.inputValue();
+      const afterLeftTo = await toField.inputValue();
+      const afterLeftFromTime = new Date(afterLeftFrom).getTime();
+      const afterLeftToTime = new Date(afterLeftTo).getTime();
+
+      expect(afterLeftFromTime, 'panned forward').toBeGreaterThan(initialFromTime);
+      expect(afterLeftToTime, 'panned forward').toBeGreaterThan(initialToTime);
+    });
+  });
+});
diff --git a/packages/grafana-ui/src/components/uPlot/config/UPlotConfigBuilder.ts b/packages/grafana-ui/src/components/uPlot/config/UPlotConfigBuilder.ts
index 2431d9ecff5..27322714477 100644
--- a/packages/grafana-ui/src/components/uPlot/config/UPlotConfigBuilder.ts
+++ b/packages/grafana-ui/src/components/uPlot/config/UPlotConfigBuilder.ts
@@ -29,6 +29,8 @@ const cursorDefaults: Cursor = {
 type PrepData = (frames: DataFrame[]) => AlignedData | FacetedData;
 type PreDataStacked = (frames: DataFrame[], stackingGroups: StackingGroup[]) => AlignedData | FacetedData;
 
+type PlotState = { isPanning: false } | { isPanning: true; min: number; max: number };
+
 export class UPlotConfigBuilder {
   readonly uid = Math.random().toString(36).slice(2);
 
@@ -47,6 +49,7 @@ export class UPlotConfigBuilder {
   // to prevent more than one threshold per scale
   private thresholds: Record<string, UPlotThresholdOptions> = {};
   private padding?: Padding = undefined;
+  private state: PlotState = { isPanning: false };
 
   private cachedConfig?: PlotConfig;
 
@@ -59,6 +62,14 @@ export class UPlotConfigBuilder {
   // Exposed to let the container know the primary scale keys
   scaleKeys: [string, string] = ['', ''];
 
+  setState(state: PlotState) {
+    this.state = merge({}, this.state, state);
+  }
+
+  getState() {
+    return this.state;
+  }
+
   addHook<T extends keyof Hooks.Defs>(type: T, hook: Hooks.Defs[T]) {
     pluginLog('UPlotConfigBuilder', false, 'addHook', type);
 
diff --git a/packages/grafana-ui/src/components/uPlot/plugins/XAxisInteractionAreaPlugin.test.tsx b/packages/grafana-ui/src/components/uPlot/plugins/XAxisInteractionAreaPlugin.test.tsx
new file mode 100644
index 00000000000..d9a6e787251
--- /dev/null
+++ b/packages/grafana-ui/src/components/uPlot/plugins/XAxisInteractionAreaPlugin.test.tsx
@@ -0,0 +1,159 @@
+import uPlot from 'uplot';
+
+import { UPlotConfigBuilder } from '../config/UPlotConfigBuilder';
+
+import { calculatePanRange, setupXAxisPan } from './XAxisInteractionAreaPlugin';
+
+const asUPlot = (partial: Partial<uPlot>) => partial as uPlot;
+const asConfigBuilder = (partial: Partial<UPlotConfigBuilder>) => partial as UPlotConfigBuilder;
+
+const createMockXAxis = () => {
+  const element = document.createElement('div');
+  element.classList.add('u-axis');
+  return element;
+};
+
+const createMockConfigBuilder = () => {
+  return {
+    setState: jest.fn(),
+    getState: jest.fn(() => ({ isPanning: false })),
+  } satisfies Partial<UPlotConfigBuilder>;
+};
+
+const createMockUPlot = (xAxisElement: HTMLElement) => {
+  const root = document.createElement('div');
+  root.appendChild(xAxisElement);
+
+  const over = document.createElement('div');
+  Object.defineProperty(over, 'getBoundingClientRect', {
+    value: () => ({ left: 0, top: 0, width: 800, height: 400 }),
+  });
+
+  return {
+    root,
+    over,
+    bbox: { width: 800, height: 400, left: 0, top: 0 },
+    scales: {
+      x: {
+        min: 1000,
+        max: 2000,
+        range: () => [1000, 2000],
+      },
+    },
+    setScale: jest.fn(),
+  } satisfies Partial<uPlot>;
+};
+
+describe('XAxisInteractionAreaPlugin', () => {
+  beforeEach(() => {
+    jest.clearAllMocks();
+  });
+
+  describe('calculatePanRange', () => {
+    it('should calculate pan range correctly for positive and negative drag', () => {
+      const timeFrom = 1000;
+      const timeTo = 2000;
+      const plotWidth = 800;
+
+      const dragRight100px = calculatePanRange(timeFrom, timeTo, 100, plotWidth);
+      expect(dragRight100px.from).toBeCloseTo(875, 1);
+      expect(dragRight100px.to).toBeCloseTo(1875, 1);
+
+      const dragLeft100px = calculatePanRange(timeFrom, timeTo, -100, plotWidth);
+      expect(dragLeft100px.from).toBeCloseTo(1125, 1);
+      expect(dragLeft100px.to).toBeCloseTo(2125, 1);
+    });
+
+    it('should return original range when not dragged', () => {
+      const noDrag = calculatePanRange(1000, 2000, 0, 800);
+      expect(noDrag.from).toBe(1000);
+      expect(noDrag.to).toBe(2000);
+    });
+  });
+
+  describe('setupXAxisPan', () => {
+    let mockQueryZoom: jest.Mock;
+    let mockConfigBuilder: ReturnType<typeof createMockConfigBuilder>;
+    let xAxisElement: HTMLElement;
+    let mockUPlot: ReturnType<typeof createMockUPlot>;
+
+    beforeEach(() => {
+      mockQueryZoom = jest.fn();
+      mockConfigBuilder = createMockConfigBuilder();
+      xAxisElement = createMockXAxis();
+      mockUPlot = createMockUPlot(xAxisElement);
+      document.body.appendChild(mockUPlot.root!);
+    });
+
+    afterEach(() => {
+      document.body.innerHTML = '';
+      jest.clearAllMocks();
+    });
+
+    it('should handle missing x-axis element gracefully', () => {
+      const emptyRoot = document.createElement('div');
+      const emptyUPlot = { ...mockUPlot, root: emptyRoot };
+
+      expect(() => setupXAxisPan(asUPlot(emptyUPlot), asConfigBuilder(mockConfigBuilder), mockQueryZoom)).not.toThrow();
+    });
+
+    it('should show grab cursor on hover and grabbing during drag', () => {
+      setupXAxisPan(asUPlot(mockUPlot), asConfigBuilder(mockConfigBuilder), mockQueryZoom);
+
+      xAxisElement.dispatchEvent(new MouseEvent('mouseenter'));
+      expect(xAxisElement).toHaveStyle({ cursor: 'grab' });
+
+      xAxisElement.dispatchEvent(new MouseEvent('mousedown', { clientX: 400, bubbles: true }));
+      expect(xAxisElement).toHaveStyle({ cursor: 'grabbing' });
+
+      document.dispatchEvent(new MouseEvent('mouseup', { clientX: 350, bubbles: true }));
+      expect(xAxisElement).toHaveStyle({ cursor: 'grab' });
+    });
+
+    it('should update scale during drag and call queryZoom on completion', () => {
+      setupXAxisPan(asUPlot(mockUPlot), asConfigBuilder(mockConfigBuilder), mockQueryZoom);
+
+      xAxisElement.dispatchEvent(new MouseEvent('mousedown', { clientX: 400, bubbles: true }));
+      document.dispatchEvent(new MouseEvent('mousemove', { clientX: 350, bubbles: true }));
+
+      const expectedRange = calculatePanRange(1000, 2000, -50, 800);
+
+      expect(mockUPlot.setScale).toHaveBeenCalledWith('x', {
+        min: expectedRange.from,
+        max: expectedRange.to,
+      });
+
+      document.dispatchEvent(new MouseEvent('mouseup', { clientX: 350, bubbles: true }));
+
+      expect(mockQueryZoom).toHaveBeenCalledWith(expectedRange);
+    });
+
+    it('should not call queryZoom when drag distance is below threshold', () => {
+      setupXAxisPan(asUPlot(mockUPlot), asConfigBuilder(mockConfigBuilder), mockQueryZoom);
+
+      xAxisElement.dispatchEvent(new MouseEvent('mousedown', { clientX: 400, bubbles: true }));
+      document.dispatchEvent(new MouseEvent('mouseup', { clientX: 402, bubbles: true }));
+
+      expect(mockQueryZoom).not.toHaveBeenCalled();
+    });
+
+    it('should set isPanning state during drag and clear on mouseup', () => {
+      setupXAxisPan(asUPlot(mockUPlot), asConfigBuilder(mockConfigBuilder), mockQueryZoom);
+
+      xAxisElement.dispatchEvent(new MouseEvent('mousedown', { clientX: 400, bubbles: true }));
+      document.dispatchEvent(new MouseEvent('mousemove', { clientX: 350, bubbles: true }));
+
+      const expectedRange = calculatePanRange(1000, 2000, -50, 800);
+
+      expect(mockConfigBuilder.setState).toHaveBeenCalledWith({
+        isPanning: true,
+        min: expectedRange.from,
+        max: expectedRange.to,
+      });
+
+      document.dispatchEvent(new MouseEvent('mouseup', { clientX: 350, bubbles: true }));
+
+      expect(mockConfigBuilder.setState).toHaveBeenCalledWith({ isPanning: false });
+    });
+  });
+});
diff --git a/packages/grafana-ui/src/components/uPlot/plugins/XAxisInteractionAreaPlugin.tsx b/packages/grafana-ui/src/components/uPlot/plugins/XAxisInteractionAreaPlugin.tsx
new file mode 100644
index 00000000000..694f372307d
--- /dev/null
+++ b/packages/grafana-ui/src/components/uPlot/plugins/XAxisInteractionAreaPlugin.tsx
@@ -0,0 +1,164 @@
+import { useLayoutEffect } from 'react';
+import uPlot from 'uplot';
+
+import { getFeatureToggle } from '../../../utils/featureToggle';
+import { UPlotConfigBuilder } from '../config/UPlotConfigBuilder';
+
+const MIN_PAN_DIST = 5;
+
+/**
+ * Calculates the new time range after a pan operation.
+ *
+ * @returns Object containing the new from and to time values
+ * @internal - exported for testing only
+ */
+export const calculatePanRange = (
+  timeFrom: number,
+  timeTo: number,
+  dragPixels: number,
+  plotWidth: number
+): { from: number; to: number } => {
+  const unitsPerPx = (timeTo - timeFrom) / (plotWidth / uPlot.pxRatio);
+  const timeShift = dragPixels * unitsPerPx;
+
+  return {
+    from: timeFrom - timeShift,
+    to: timeTo - timeShift,
+  };
+};
+
+/**
+ * Enables panning the time range by click and dragging x-axis labels with the mouse.
+ * Provides visual feedback (grab/grabbing cursor) and real-time grid updates during drag.
+ *
+ * @returns Cleanup function to remove event listeners
+ * @internal - exported for testing only
+ */
+export const setupXAxisPan = (
+  u: uPlot,
+  config: UPlotConfigBuilder,
+  queryZoom: (range: { from: number; to: number }) => void
+): (() => void) => {
+  let xAxes = u.root.querySelectorAll('.u-axis');
+  let xAxis = xAxes[0];
+
+  if (!xAxis || !(xAxis instanceof HTMLElement)) {
+    return () => {};
+  }
+
+  const xAxisEl = xAxis;
+
+  let activeMoveListener: ((e: MouseEvent) => void) | null = null;
+  let activeUpListener: ((e: MouseEvent) => void) | null = null;
+
+  const handleMouseEnter = () => {
+    xAxisEl.style.cursor = 'grab';
+  };
+
+  const handleMouseLeave = () => {
+    xAxisEl.style.cursor = '';
+  };
+
+  const handleMouseDown = (e: Event) => {
+    if (!(e instanceof MouseEvent)) {
+      return;
+    }
+    e.preventDefault();
+
+    xAxisEl.style.cursor = 'grabbing';
+
+    let xScale = u.scales.x;
+
+    let rect = u.over.getBoundingClientRect();
+    let startX = e.clientX - rect.left;
+    let startMin = xScale.min!;
+    let startMax = xScale.max!;
+
+    const onMove = (e: MouseEvent) => {
+      e.preventDefault();
+
+      let currentX = e.clientX - rect.left;
+      let dragPixels = currentX - startX;
+
+      const { from, to } = calculatePanRange(startMin, startMax, dragPixels, u.bbox.width);
+
+      config.setState({ isPanning: true, min: from, max: to });
+
+      u.setScale('x', {
+        min: from,
+        max: to,
+      });
+    };
+
+    const onUp = (e: MouseEvent) => {
+      let endX = e.clientX - rect.left;
+      let dragPixels = endX - startX;
+
+      xAxisEl.style.cursor = 'grab';
+
+      config.setState({ isPanning: false });
+
+      if (Math.abs(dragPixels) >= MIN_PAN_DIST) {
+        const newRange = calculatePanRange(startMin, startMax, dragPixels, u.bbox.width);
+        queryZoom(newRange);
+      }
+
+      document.removeEventListener('mousemove', onMove);
+      document.removeEventListener('mouseup', onUp);
+      activeMoveListener = null;
+      activeUpListener = null;
+    };
+
+    activeMoveListener = onMove;
+    activeUpListener = onUp;
+
+    document.addEventListener('mousemove', onMove);
+    document.addEventListener('mouseup', onUp);
+  };
+
+  xAxisEl.addEventListener('mouseenter', handleMouseEnter);
+  xAxisEl.addEventListener('mouseleave', handleMouseLeave);
+  xAxisEl.addEventListener('mousedown', handleMouseDown);
+
+  return () => {
+    xAxisEl.removeEventListener('mouseenter', handleMouseEnter);
+    xAxisEl.removeEventListener('mouseleave', handleMouseLeave);
+    xAxisEl.removeEventListener('mousedown', handleMouseDown);
+
+    if (activeMoveListener) {
+      document.removeEventListener('mousemove', activeMoveListener);
+    }
+    if (activeUpListener) {
+      document.removeEventListener('mouseup', activeUpListener);
+    }
+  };
+};
+
+export interface XAxisInteractionAreaPluginProps {
+  config: UPlotConfigBuilder;
+  queryZoom?: (range: { from: number; to: number }) => void;
+}
+
+/**
+ * Plugin for handling x-axis area interactions, such as time range panning.
+ * Properly manages event listener lifecycle to prevent memory leaks.
+ */
+export const XAxisInteractionAreaPlugin = ({ config, queryZoom }: XAxisInteractionAreaPluginProps) => {
+  useLayoutEffect(() => {
+    let cleanup: (() => void) | undefined;
+
+    config.addHook('init', (u) => {
+      if (queryZoom != null && getFeatureToggle('timeRangePan')) {
+        cleanup = setupXAxisPan(u, config, queryZoom);
+      }
+    });
+
+    return () => {
+      if (cleanup) {
+        cleanup();
+      }
+    };
+  }, [config, queryZoom]);
+
+  return null;
+};
diff --git a/packages/grafana-ui/src/index.ts b/packages/grafana-ui/src/index.ts
index b9082ae9901..b46ce1d33bb 100644
--- a/packages/grafana-ui/src/index.ts
+++ b/packages/grafana-ui/src/index.ts
@@ -353,6 +353,7 @@ export { EventsCanvas } from './components/uPlot/geometries/EventsCanvas';
 export { TooltipPlugin2 } from './components/uPlot/plugins/TooltipPlugin2';
 export { EventBusPlugin } from './components/uPlot/plugins/EventBusPlugin';
 export { KeyboardPlugin } from './components/uPlot/plugins/KeyboardPlugin';
+export { XAxisInteractionAreaPlugin } from './components/uPlot/plugins/XAxisInteractionAreaPlugin';
 
 export { type PlotTooltipInterpolator, type PlotSelection, FIXED_UNIT } from './components/uPlot/types';
 export { type UPlotConfigPrepFn } from './components/uPlot/config/UPlotConfigBuilder';
diff --git a/public/app/core/components/TimeSeries/utils.ts b/public/app/core/components/TimeSeries/utils.ts
index 82c18cdd359..f81de163b7f 100644
--- a/public/app/core/components/TimeSeries/utils.ts
+++ b/public/app/core/components/TimeSeries/utils.ts
@@ -136,6 +136,10 @@ export const preparePlotConfigBuilder: UPlotConfigPrepFn = ({
       direction: isHorizontal ? ScaleDirection.Right : ScaleDirection.Up,
       isTime: true,
       range: () => {
+        const state = builder.getState();
+        if (state.isPanning) {
+          return [state.min, state.max];
+        }
         const r = getTimeRange();
         return [r.from.valueOf(), r.to.valueOf()];
       },
diff --git a/public/app/plugins/panel/timeseries/TimeSeriesPanel.tsx b/public/app/plugins/panel/timeseries/TimeSeriesPanel.tsx
index bb0a93310a8..24f6be1672e 100644
--- a/public/app/plugins/panel/timeseries/TimeSeriesPanel.tsx
+++ b/public/app/plugins/panel/timeseries/TimeSeriesPanel.tsx
@@ -12,7 +12,13 @@ import {
 } from '@grafana/data';
 import { PanelDataErrorView } from '@grafana/runtime';
 import { TooltipDisplayMode, VizOrientation } from '@grafana/schema';
-import { EventBusPlugin, KeyboardPlugin, TooltipPlugin2, usePanelContext } from '@grafana/ui';
+import {
+  EventBusPlugin,
+  KeyboardPlugin,
+  TooltipPlugin2,
+  XAxisInteractionAreaPlugin,
+  usePanelContext,
+} from '@grafana/ui';
 import { TimeRange2, TooltipHoverMode } from '@grafana/ui/internal';
 import { TimeSeries } from 'app/core/components/TimeSeries/TimeSeries';
 import { config } from 'app/core/config';
@@ -141,6 +147,7 @@ export const TimeSeriesPanel = ({
             {cursorSync !== DashboardCursorSync.Off && (
               <EventBusPlugin config={uplotConfig} eventBus={eventBus} frame={alignedFrame} />
             )}
+            <XAxisInteractionAreaPlugin config={uplotConfig} queryZoom={onChangeTimeRange} />
             {options.tooltip.mode !== TooltipDisplayMode.None && (
               <TooltipPlugin2
                 config={uplotConfig}