diff --git a/packages/grafana-ui/src/components/Combobox/Combobox.tsx b/packages/grafana-ui/src/components/Combobox/Combobox.tsx
index c3940a7fed1..511f1438a4d 100644
--- a/packages/grafana-ui/src/components/Combobox/Combobox.tsx
+++ b/packages/grafana-ui/src/components/Combobox/Combobox.tsx
@@ -27,7 +27,7 @@ export type ComboboxOption<T extends string | number = string> = {
 
 // TODO: It would be great if ComboboxOption["label"] was more generic so that if consumers do pass it in (for async),
 // then the onChange handler emits ComboboxOption with the label as non-undefined.
-interface ComboboxBaseProps<T extends string | number>
+export interface ComboboxBaseProps<T extends string | number>
   extends Pick<
     InputProps,
     'placeholder' | 'autoFocus' | 'id' | 'aria-labelledby' | 'disabled' | 'loading' | 'invalid'
@@ -66,7 +66,7 @@ type ClearableConditionals<T extends number | string> =
     }
   | { isClearable?: false; onChange: (option: ComboboxOption<T>) => void };
 
-type AutoSizeConditionals =
+export type AutoSizeConditionals =
   | {
       width: 'auto';
       /**
@@ -86,7 +86,7 @@ type AutoSizeConditionals =
 
 type ComboboxProps<T extends string | number> = ComboboxBaseProps<T> & AutoSizeConditionals & ClearableConditionals<T>;
 
-function itemToString<T extends string | number>(item?: ComboboxOption<T> | null) {
+export function itemToString<T extends string | number>(item?: ComboboxOption<T> | null) {
   if (!item) {
     return '';
   }
diff --git a/packages/grafana-ui/src/components/Combobox/MultiCombobox.internal.story.tsx b/packages/grafana-ui/src/components/Combobox/MultiCombobox.internal.story.tsx
new file mode 100644
index 00000000000..0259c72d2ba
--- /dev/null
+++ b/packages/grafana-ui/src/components/Combobox/MultiCombobox.internal.story.tsx
@@ -0,0 +1,29 @@
+import type { Meta, StoryObj } from '@storybook/react';
+
+import { MultiCombobox } from './MultiCombobox';
+import mdx from './MultiCombobox.mdx';
+
+const meta: Meta<typeof MultiCombobox> = {
+  title: 'Forms/MultiCombobox',
+  component: MultiCombobox,
+  parameters: {
+    docs: {
+      page: mdx,
+    },
+  },
+};
+
+export default meta;
+
+type Story = StoryObj<typeof MultiCombobox>;
+
+export const Basic: Story = {
+  args: {
+    options: [
+      { label: 'Option 1', value: 'option1' },
+      { label: 'Option 2', value: 'option2' },
+      { label: 'Option 3', value: 'option3' },
+    ],
+    placeholder: 'Select multiple options...',
+  },
+};
diff --git a/packages/grafana-ui/src/components/Combobox/MultiCombobox.mdx b/packages/grafana-ui/src/components/Combobox/MultiCombobox.mdx
new file mode 100644
index 00000000000..e69de29bb2d
diff --git a/packages/grafana-ui/src/components/Combobox/MultiCombobox.tsx b/packages/grafana-ui/src/components/Combobox/MultiCombobox.tsx
new file mode 100644
index 00000000000..f7d8d7de3bc
--- /dev/null
+++ b/packages/grafana-ui/src/components/Combobox/MultiCombobox.tsx
@@ -0,0 +1,138 @@
+import { useCombobox, useMultipleSelection } from 'downshift';
+import { useState } from 'react';
+
+import { useStyles2 } from '../../themes';
+import { Checkbox } from '../Forms/Checkbox';
+import { Portal } from '../Portal/Portal';
+
+import { ComboboxOption, ComboboxBaseProps, AutoSizeConditionals, itemToString } from './Combobox';
+import { OptionListItem } from './OptionListItem';
+import { ValuePill } from './ValuePill';
+import { getMultiComboboxStyles } from './getMultiComboboxStyles';
+
+interface MultiComboboxBaseProps<T extends string | number> extends Omit<ComboboxBaseProps<T>, 'value' | 'onChange'> {
+  value?: string | Array<ComboboxOption<T>>;
+  onChange: (items?: Array<ComboboxOption<T>>) => void;
+}
+
+type MultiComboboxProps<T extends string | number> = MultiComboboxBaseProps<T> & AutoSizeConditionals;
+
+export const MultiCombobox = <T extends string | number>(props: MultiComboboxProps<T>) => {
+  const { options, placeholder } = props;
+
+  const multiStyles = useStyles2(getMultiComboboxStyles);
+
+  const isAsync = typeof options === 'function';
+
+  const [items, _baseSetItems] = useState(isAsync ? [] : options);
+  const [isOpen, setIsOpen] = useState(false);
+  const [selectedItems, setSelectedItems] = useState<Array<ComboboxOption<T>>>([]);
+
+  const [inputValue, setInputValue] = useState('');
+
+  const { getSelectedItemProps, getDropdownProps, removeSelectedItem } = useMultipleSelection({
+    selectedItems, //initally selected items,
+    onStateChange: ({ type, selectedItems: newSelectedItems }) => {
+      switch (type) {
+        case useMultipleSelection.stateChangeTypes.SelectedItemKeyDownBackspace:
+        case useMultipleSelection.stateChangeTypes.SelectedItemKeyDownDelete:
+        case useMultipleSelection.stateChangeTypes.DropdownKeyDownBackspace:
+        case useMultipleSelection.stateChangeTypes.FunctionRemoveSelectedItem:
+          if (newSelectedItems) {
+            setSelectedItems(newSelectedItems);
+          }
+          break;
+        default:
+          break;
+      }
+    },
+  });
+
+  const {
+    //getToggleButtonProps,
+    //getLabelProps,
+    getMenuProps,
+    getInputProps,
+    highlightedIndex,
+    getItemProps,
+    //selectedItem,
+  } = useCombobox({
+    isOpen,
+    items,
+    itemToString,
+    inputValue,
+    //defaultHighlightedIndex: 0,
+    selectedItem: null,
+
+    onStateChange: ({ inputValue: newInputValue, type, selectedItem: newSelectedItem }) => {
+      switch (type) {
+        case useCombobox.stateChangeTypes.InputKeyDownEnter:
+        case useCombobox.stateChangeTypes.ItemClick:
+          if (newSelectedItem) {
+            const isAlreadySelected = selectedItems.some((opt) => opt.value === newSelectedItem.value);
+            if (!isAlreadySelected) {
+              setSelectedItems([...selectedItems, newSelectedItem]);
+              break;
+            }
+            removeSelectedItem(newSelectedItem);
+          }
+          break;
+        case useCombobox.stateChangeTypes.InputBlur:
+          setIsOpen(false);
+          setInputValue('');
+          break;
+        case useCombobox.stateChangeTypes.InputChange:
+          setInputValue(newInputValue ?? '');
+          break;
+        default:
+          break;
+      }
+    },
+  });
+
+  return (
+    <div className={multiStyles.wrapper}>
+      <span className={multiStyles.pillWrapper}>
+        {selectedItems.map((item, index) => (
+          <ValuePill
+            onRemove={() => {
+              removeSelectedItem(item);
+            }}
+            key={`${item.value}${index}`}
+            {...getSelectedItemProps({ selectedItem: item, index })}
+          >
+            {itemToString(item)}
+          </ValuePill>
+        ))}
+      </span>
+      <input
+        className={multiStyles.input}
+        {...getInputProps(getDropdownProps({ preventKeyAction: isOpen, placeholder, onFocus: () => setIsOpen(true) }))}
+      />
+      <div {...getMenuProps()}>
+        <Portal>
+          {isOpen && (
+            <div>
+              {items.map((item, index) => {
+                const itemProps = getItemProps({ item, index });
+                const isSelected = selectedItems.some((opt) => opt.value === item.value);
+                return (
+                  <li
+                    key={item.value}
+                    {...itemProps}
+                    style={highlightedIndex === index ? { backgroundColor: 'blue' } : {}}
+                  >
+                    {' '}
+                    {/* Add styling with virtualization */}
+                    <Checkbox key={`${item.value}${index}`} value={isSelected} />
+                    <OptionListItem option={item} />
+                  </li>
+                );
+              })}
+            </div>
+          )}
+        </Portal>
+      </div>
+    </div>
+  );
+};
diff --git a/packages/grafana-ui/src/components/Combobox/OptionListItem.tsx b/packages/grafana-ui/src/components/Combobox/OptionListItem.tsx
new file mode 100644
index 00000000000..1138a60c282
--- /dev/null
+++ b/packages/grafana-ui/src/components/Combobox/OptionListItem.tsx
@@ -0,0 +1,18 @@
+import { useStyles2 } from '../../themes';
+
+import { ComboboxOption } from './Combobox';
+import { getComboboxStyles } from './getComboboxStyles';
+
+interface Props {
+  option: ComboboxOption<string | number>;
+}
+
+export const OptionListItem = ({ option }: Props) => {
+  const styles = useStyles2(getComboboxStyles);
+  return (
+    <div className={styles.optionBody}>
+      <span className={styles.optionLabel}>{option.label ?? option.value}</span>
+      {option.description && <span className={styles.optionDescription}>{option.description}</span>}
+    </div>
+  );
+};
diff --git a/packages/grafana-ui/src/components/Combobox/ValuePill.tsx b/packages/grafana-ui/src/components/Combobox/ValuePill.tsx
new file mode 100644
index 00000000000..3f1a2dce3d8
--- /dev/null
+++ b/packages/grafana-ui/src/components/Combobox/ValuePill.tsx
@@ -0,0 +1,50 @@
+import { css } from '@emotion/css';
+import { forwardRef } from 'react';
+
+import { GrafanaTheme2 } from '@grafana/data';
+
+import { useStyles2 } from '../../themes';
+import { IconButton } from '../IconButton/IconButton';
+
+interface ValuePillProps {
+  children: string;
+  onRemove: () => void;
+}
+
+export const ValuePill = forwardRef<HTMLSpanElement, ValuePillProps>(({ children, onRemove, ...rest }, ref) => {
+  const styles = useStyles2(getValuePillStyles);
+  return (
+    <span className={styles.wrapper} {...rest} ref={ref}>
+      {children}
+      <span className={styles.separator} />
+      <IconButton
+        name="times"
+        size="md"
+        aria-label={`Remove ${children}`}
+        onClick={(e) => {
+          e.stopPropagation();
+          onRemove();
+        }}
+      />
+    </span>
+  );
+});
+
+const getValuePillStyles = (theme: GrafanaTheme2) => ({
+  wrapper: css({
+    display: 'inline-flex',
+    gap: theme.spacing(0.5),
+    borderRadius: theme.shape.radius.default,
+    color: theme.colors.text.primary,
+    background: theme.colors.background.secondary,
+    padding: theme.spacing(0.25),
+    fontSize: theme.typography.bodySmall.fontSize,
+  }),
+
+  separator: css({
+    background: theme.colors.border.weak,
+    width: '2px',
+    marginLeft: theme.spacing(0.25),
+    height: '100%',
+  }),
+});
diff --git a/packages/grafana-ui/src/components/Combobox/getMultiComboboxStyles.ts b/packages/grafana-ui/src/components/Combobox/getMultiComboboxStyles.ts
new file mode 100644
index 00000000000..43a8555048e
--- /dev/null
+++ b/packages/grafana-ui/src/components/Combobox/getMultiComboboxStyles.ts
@@ -0,0 +1,43 @@
+import { css, cx } from '@emotion/css';
+
+import { GrafanaTheme2 } from '@grafana/data';
+
+import { getFocusStyles } from '../../themes/mixins';
+import { getInputStyles } from '../Input/Input';
+
+export const getMultiComboboxStyles = (theme: GrafanaTheme2) => {
+  const inputStyles = getInputStyles({ theme });
+  const focusStyles = getFocusStyles(theme);
+
+  return {
+    wrapper: cx(
+      inputStyles.input,
+      css({
+        display: 'flex',
+        gap: theme.spacing(0.5),
+        padding: theme.spacing(0.5),
+        '&:focus-within': {
+          ...focusStyles,
+        },
+      })
+    ),
+    input: css({
+      border: 'none',
+      outline: 'none',
+      background: 'transparent',
+      flexGrow: 1,
+      minWidth: '0',
+      '&::placeholder': {
+        color: theme.colors.text.disabled,
+      },
+      '&:focus': {
+        outline: 'none',
+      },
+    }),
+    pillWrapper: css({
+      display: 'inline-flex',
+      flexWrap: 'wrap',
+      gap: theme.spacing(0.5),
+    }),
+  };
+};