diff --git a/public/app/features/dashboard-scene/scene/setDashboardPanelContext.test.ts b/public/app/features/dashboard-scene/scene/setDashboardPanelContext.test.ts
index 36eb42d3a05..d246ddcccd4 100644
--- a/public/app/features/dashboard-scene/scene/setDashboardPanelContext.test.ts
+++ b/public/app/features/dashboard-scene/scene/setDashboardPanelContext.test.ts
@@ -130,11 +130,16 @@ describe('setDashboardPanelContext', () => {
     it('Should add new filter set', () => {
       const { scene, context } = buildTestScene({});
 
-      context.onAddAdHocFilter!({ key: 'hello', value: 'world', operator: '=' });
+      context.onAddAdHocFilter!({ key: 'hello', value: 'world', operator: '!=' });
+      context.onAddAdHocFilter!({ key: 'hello', value: 'world2', operator: '!=' });
 
       const variable = getAdHocFilterVariableFor(scene, { uid: 'my-ds-uid' });
 
-      expect(variable.state.filters).toEqual([{ key: 'hello', value: 'world', operator: '=' }]);
+      expect(variable.state.filters).toEqual([
+        { key: 'hello', value: 'world', operator: '!=' },
+        { key: 'hello', value: 'world2', operator: '!=' },
+        ,
+      ]);
     });
 
     it('Should update and add filter to existing set', () => {
@@ -149,9 +154,9 @@ describe('setDashboardPanelContext', () => {
       expect(variable.state.filters.length).toBe(2);
 
       // Can update existing filter value without adding a new filter
-      context.onAddAdHocFilter!({ key: 'hello', value: 'world2', operator: '=' });
+      context.onAddAdHocFilter!({ key: 'hello', value: 'world', operator: '!=' });
       // Verify existing filter value updated
-      expect(variable.state.filters[1].value).toBe('world2');
+      expect(variable.state.filters[1].operator).toBe('!=');
     });
   });
 });
diff --git a/public/app/features/dashboard-scene/scene/setDashboardPanelContext.ts b/public/app/features/dashboard-scene/scene/setDashboardPanelContext.ts
index 00150b02a0a..4b141354801 100644
--- a/public/app/features/dashboard-scene/scene/setDashboardPanelContext.ts
+++ b/public/app/features/dashboard-scene/scene/setDashboardPanelContext.ts
@@ -175,23 +175,23 @@ export function getAdHocFilterVariableFor(scene: DashboardScene, ds: DataSourceR
 }
 
 function updateAdHocFilterVariable(filterVar: AdHocFiltersVariable, newFilter: AdHocFilterItem) {
-  // Check if we need to update an existing filter
-  for (const filter of filterVar.state.filters) {
-    if (filter.key === newFilter.key) {
-      filterVar.setState({
-        filters: filterVar.state.filters.map((f) => {
-          if (f.key === newFilter.key) {
-            return newFilter;
-          }
-          return f;
-        }),
-      });
-      return;
-    }
+  // This function handles 'Filter for value' and 'Filter out value' from table cell
+  // We are allowing to add filters with the same key because elastic search ds supports that
+
+  // Update is only required when we change operator and keep key and value the same
+  //   key1 = value1 -> key1 != value1
+  const filterToReplaceIndex = filterVar.state.filters.findIndex(
+    (filter) =>
+      filter.key === newFilter.key && filter.value === newFilter.value && filter.operator !== newFilter.operator
+  );
+
+  if (filterToReplaceIndex >= 0) {
+    const updatedFilters = filterVar.state.filters.slice();
+    updatedFilters.splice(filterToReplaceIndex, 1, newFilter);
+    filterVar.updateFilters(updatedFilters);
+    return;
   }
 
   // Add new filter
-  filterVar.setState({
-    filters: [...filterVar.state.filters, newFilter],
-  });
+  filterVar.updateFilters([...filterVar.state.filters, newFilter]);
 }