diff --git a/eslint-suppressions.json b/eslint-suppressions.json
index a5155bbdd95..7464e82bb3e 100644
--- a/eslint-suppressions.json
+++ b/eslint-suppressions.json
@@ -24,11 +24,6 @@
       "count": 1
     }
   },
-  "packages/grafana-data/src/dataframe/ArrayDataFrame.ts": {
-    "@typescript-eslint/no-explicit-any": {
-      "count": 1
-    }
-  },
   "packages/grafana-data/src/dataframe/CircularDataFrame.ts": {
     "@typescript-eslint/no-explicit-any": {
       "count": 1
@@ -36,7 +31,7 @@
   },
   "packages/grafana-data/src/dataframe/DataFrameView.ts": {
     "@typescript-eslint/consistent-type-assertions": {
-      "count": 2
+      "count": 1
     },
     "@typescript-eslint/no-explicit-any": {
       "count": 2
@@ -44,28 +39,23 @@
   },
   "packages/grafana-data/src/dataframe/MutableDataFrame.ts": {
     "@typescript-eslint/consistent-type-assertions": {
-      "count": 3
+      "count": 1
     },
     "@typescript-eslint/no-explicit-any": {
-      "count": 9
+      "count": 6
     }
   },
   "packages/grafana-data/src/dataframe/StreamingDataFrame.ts": {
     "@typescript-eslint/consistent-type-assertions": {
-      "count": 4
-    }
-  },
-  "packages/grafana-data/src/dataframe/processDataFrame.test.ts": {
-    "@typescript-eslint/no-explicit-any": {
-      "count": 1
+      "count": 3
     }
   },
   "packages/grafana-data/src/dataframe/processDataFrame.ts": {
     "@typescript-eslint/consistent-type-assertions": {
-      "count": 15
+      "count": 11
     },
     "@typescript-eslint/no-explicit-any": {
-      "count": 5
+      "count": 4
     }
   },
   "packages/grafana-data/src/datetime/moment_wrapper.ts": {
@@ -106,7 +96,7 @@
       "count": 1
     },
     "@typescript-eslint/no-explicit-any": {
-      "count": 5
+      "count": 4
     }
   },
   "packages/grafana-data/src/panel/registryFactories.ts": {
@@ -305,7 +295,7 @@
   },
   "packages/grafana-data/src/utils/csv.ts": {
     "@typescript-eslint/consistent-type-assertions": {
-      "count": 3
+      "count": 2
     },
     "@typescript-eslint/no-explicit-any": {
       "count": 2
@@ -347,11 +337,6 @@
       "count": 3
     }
   },
-  "packages/grafana-data/src/vector/CircularVector.ts": {
-    "@typescript-eslint/no-explicit-any": {
-      "count": 1
-    }
-  },
   "packages/grafana-data/src/vector/FunctionalVector.ts": {
     "@typescript-eslint/no-explicit-any": {
       "count": 9
@@ -769,7 +754,7 @@
   },
   "packages/grafana-ui/src/components/Modal/ModalsContext.tsx": {
     "@typescript-eslint/no-explicit-any": {
-      "count": 4
+      "count": 2
     },
     "react-prefer-function-component/react-prefer-function-component": {
       "count": 1
@@ -847,7 +832,7 @@
   },
   "packages/grafana-ui/src/components/Select/SelectBase.tsx": {
     "@typescript-eslint/consistent-type-assertions": {
-      "count": 2
+      "count": 1
     },
     "@typescript-eslint/no-explicit-any": {
       "count": 4
@@ -860,7 +845,7 @@
   },
   "packages/grafana-ui/src/components/Select/resetSelectStyles.ts": {
     "@typescript-eslint/no-explicit-any": {
-      "count": 4
+      "count": 1
     }
   },
   "packages/grafana-ui/src/components/Select/types.ts": {
@@ -875,7 +860,7 @@
   },
   "packages/grafana-ui/src/components/SingleStatShared/SingleStatBaseOptions.ts": {
     "@typescript-eslint/consistent-type-assertions": {
-      "count": 3
+      "count": 2
     },
     "@typescript-eslint/no-explicit-any": {
       "count": 13
@@ -4751,7 +4736,7 @@
   },
   "public/app/plugins/panel/live/LiveChannelEditor.tsx": {
     "@typescript-eslint/consistent-type-assertions": {
-      "count": 2
+      "count": 1
     },
     "@typescript-eslint/no-explicit-any": {
       "count": 1
diff --git a/packages/grafana-data/src/dataframe/ArrayDataFrame.ts b/packages/grafana-data/src/dataframe/ArrayDataFrame.ts
index 8817812b5bd..fdcfed8c039 100644
--- a/packages/grafana-data/src/dataframe/ArrayDataFrame.ts
+++ b/packages/grafana-data/src/dataframe/ArrayDataFrame.ts
@@ -8,14 +8,14 @@ import { guessFieldTypeForField } from './processDataFrame';
  *
  * @deprecated use arrayToDataFrame
  */
-export class ArrayDataFrame<T = any> implements DataFrame {
+export class ArrayDataFrame implements DataFrame {
   fields: Field[] = [];
   length = 0;
   name?: string;
   refId?: string;
   meta?: QueryResultMeta;
 
-  constructor(source: T[], names?: string[]) {
+  constructor(source: unknown[], names?: string[]) {
     return arrayToDataFrame(source, names); // returns a standard DataFrame
   }
 }
@@ -27,7 +27,7 @@ export class ArrayDataFrame<T = any> implements DataFrame {
  *
  * @public
  */
-export function arrayToDataFrame(source: Array<Record<string, unknown>> | unknown[], names?: string[]): DataFrame {
+export function arrayToDataFrame(source: unknown[], names?: string[]): DataFrame {
   const df: DataFrame = {
     fields: [],
     length: source.length,
diff --git a/packages/grafana-data/src/dataframe/DataFrameView.ts b/packages/grafana-data/src/dataframe/DataFrameView.ts
index d4d3c157d62..e911748fa39 100644
--- a/packages/grafana-data/src/dataframe/DataFrameView.ts
+++ b/packages/grafana-data/src/dataframe/DataFrameView.ts
@@ -23,7 +23,7 @@ export class DataFrameView<T extends object = any> extends FunctionalVector<T> {
   constructor(private data: DataFrame) {
     super();
     const obj = {} as T;
-    const fields = {} as any;
+    const fields: any = {};
 
     for (let i = 0; i < data.fields.length; i++) {
       const field = data.fields[i];
diff --git a/packages/grafana-data/src/dataframe/MutableDataFrame.ts b/packages/grafana-data/src/dataframe/MutableDataFrame.ts
index 4437aa44b5e..6ac9b79e38a 100644
--- a/packages/grafana-data/src/dataframe/MutableDataFrame.ts
+++ b/packages/grafana-data/src/dataframe/MutableDataFrame.ts
@@ -13,6 +13,8 @@ export type MutableField<T = any> = Field<T>;
 /** @deprecated */
 type MutableVectorCreator = (buffer?: unknown[]) => unknown[];
 
+type Parser = (v: string) => unknown;
+
 export const MISSING_VALUE = undefined; // Treated as connected in new graph panel
 
 /**
@@ -149,14 +151,14 @@ export class MutableDataFrame<T = any> extends FunctionalVector<T> implements Da
     }
   }
 
-  private parsers: Map<Field, (v: string) => any> | undefined = undefined;
+  private parsers: Map<Field, Parser> | undefined = undefined;
 
   /**
    * @deprecated unclear if this is actually used
    */
-  setParser(field: Field, parser: (v: string) => any) {
+  setParser(field: Field, parser: Parser) {
     if (!this.parsers) {
-      this.parsers = new Map<Field, (v: string) => any>();
+      this.parsers = new Map<Field, Parser>();
     }
     this.parsers.set(field, parser);
     return parser;
@@ -222,7 +224,7 @@ export class MutableDataFrame<T = any> extends FunctionalVector<T> implements Da
    */
   add(value: T): void {
     // Will add one value for every field
-    const obj = value as any;
+    const obj: any = value;
     for (const field of this.fields) {
       let val = obj[field.name];
 
@@ -243,7 +245,7 @@ export class MutableDataFrame<T = any> extends FunctionalVector<T> implements Da
       throw new Error('Unable to set value beyond current length');
     }
 
-    const obj = (value as Record<string, unknown>) || {};
+    const obj: Record<string, unknown> = value || {};
     for (const field of this.fields) {
       field.values[index] = obj[field.name];
     }
diff --git a/packages/grafana-data/src/dataframe/StreamingDataFrame.ts b/packages/grafana-data/src/dataframe/StreamingDataFrame.ts
index bb410406ed9..8d37543f73e 100644
--- a/packages/grafana-data/src/dataframe/StreamingDataFrame.ts
+++ b/packages/grafana-data/src/dataframe/StreamingDataFrame.ts
@@ -420,9 +420,7 @@ export class StreamingDataFrame implements DataFrame {
   };
 
   getMatchingFieldIndexes = (fieldPredicate: (f: Field) => boolean): number[] =>
-    this.fields
-      .map((f, index) => (fieldPredicate(f) ? index : undefined))
-      .filter((val) => val !== undefined) as number[];
+    this.fields.map((f, index) => (fieldPredicate(f) ? index : undefined)).filter((val) => val !== undefined);
 
   getValuesFromLastPacket = (): unknown[][] =>
     this.fields.map((f) => {
diff --git a/packages/grafana-data/src/dataframe/processDataFrame.test.ts b/packages/grafana-data/src/dataframe/processDataFrame.test.ts
index 5c7593e91c0..bb9ffefefcd 100644
--- a/packages/grafana-data/src/dataframe/processDataFrame.test.ts
+++ b/packages/grafana-data/src/dataframe/processDataFrame.test.ts
@@ -348,11 +348,11 @@ describe('SeriesData backwards compatibility', () => {
     expect(isDataFrame(timeseries)).toBeFalsy();
     expect(isDataFrame(series)).toBeTruthy();
 
-    const roundtrip = toLegacyResponseData(series) as any;
+    const roundtrip = toLegacyResponseData(series);
     expect(isDataFrame(roundtrip)).toBeFalsy();
-    expect(roundtrip.type).toBe('docs');
-    expect(roundtrip.target).toBe('docs');
-    expect(roundtrip.filterable).toBeTruthy();
+    expect('type' in roundtrip && roundtrip.type).toBe('docs');
+    expect('target' in roundtrip && roundtrip.target).toBe('docs');
+    expect('filterable' in roundtrip && roundtrip.filterable).toBeTruthy();
   });
 });
 
diff --git a/packages/grafana-data/src/dataframe/processDataFrame.ts b/packages/grafana-data/src/dataframe/processDataFrame.ts
index 14621547725..c3fd65486c7 100644
--- a/packages/grafana-data/src/dataframe/processDataFrame.ts
+++ b/packages/grafana-data/src/dataframe/processDataFrame.ts
@@ -26,13 +26,13 @@ import { dataFrameFromJSON } from './DataFrameJSON';
 function convertTableToDataFrame(table: TableData): DataFrame {
   const fields = table.columns.map((c) => {
     // TODO: should be Column but type does not exists there so not sure whats up here.
-    const { text, type, ...disp } = c as any;
+    const { text, type, ...disp } = c as Column & { type?: FieldType };
     const values: unknown[] = [];
     return {
-      name: text?.length ? text : c, // rename 'text' to the 'name' field
-      config: (disp || {}) as FieldConfig,
+      name: text ?? c, // rename 'text' to the 'name' field
+      config: disp || {},
       values,
-      type: type && Object.values(FieldType).includes(type as FieldType) ? (type as FieldType) : FieldType.other,
+      type: type && Object.values(FieldType).includes(type) ? type : FieldType.other,
     };
   });
 
@@ -400,8 +400,9 @@ export const toLegacyResponseData = (frame: DataFrame): TimeSeries | TableData =
       if (config) {
         // keep unit etc
         const { ...column } = config;
-        (column as Column).text = name;
-        return column as Column;
+        const result = column as Column;
+        result.text = name;
+        return result;
       }
       return { text: name };
     }),
diff --git a/packages/grafana-data/src/panel/PanelPlugin.ts b/packages/grafana-data/src/panel/PanelPlugin.ts
index 61985074be9..4822d4c6acb 100644
--- a/packages/grafana-data/src/panel/PanelPlugin.ts
+++ b/packages/grafana-data/src/panel/PanelPlugin.ts
@@ -122,11 +122,6 @@ export class PanelPlugin<
     alertStates: false,
   };
 
-  /**
-   * Legacy angular ctrl. If this exists it will be used instead of the panel
-   */
-  angularPanelCtrl?: any;
-
   constructor(panel: ComponentType<PanelProps<TOptions>> | null) {
     super();
     this.panel = panel;
diff --git a/packages/grafana-data/src/utils/csv.ts b/packages/grafana-data/src/utils/csv.ts
index 7c225e47ac0..9823aa4c550 100644
--- a/packages/grafana-data/src/utils/csv.ts
+++ b/packages/grafana-data/src/utils/csv.ts
@@ -115,7 +115,7 @@ export class CSVReader {
                   if (!fields[j].config) {
                     fields[j].config = {};
                   }
-                  const disp = fields[j].config as any; // any lets name lookup
+                  const disp: any = fields[j].config; // any lets name lookup
                   disp[k] = j === 0 ? v : line[j];
                 }
               }
diff --git a/packages/grafana-data/src/utils/throwIfAngular.test.ts b/packages/grafana-data/src/utils/throwIfAngular.test.ts
index 8cdbae71cd9..8b17e2f10e6 100644
--- a/packages/grafana-data/src/utils/throwIfAngular.test.ts
+++ b/packages/grafana-data/src/utils/throwIfAngular.test.ts
@@ -33,6 +33,7 @@ describe('throwIfAngular', () => {
 
   it('should throw if angular panel', () => {
     const underTest = new PanelPlugin(null);
+    // @ts-expect-error
     underTest.angularPanelCtrl = {};
     expect(() => throwIfAngular(underTest)).toThrow('Angular plugins are not supported');
   });
diff --git a/packages/grafana-data/src/vector/CircularVector.ts b/packages/grafana-data/src/vector/CircularVector.ts
index 221f7c488e5..70b570630bc 100644
--- a/packages/grafana-data/src/vector/CircularVector.ts
+++ b/packages/grafana-data/src/vector/CircularVector.ts
@@ -16,7 +16,7 @@ interface CircularOptions<T> {
  * @public
  * @deprecated use a simple Arrays
  */
-export class CircularVector<T = any> extends FunctionalVector<T> {
+export class CircularVector<T = unknown> extends FunctionalVector<T> {
   private buffer: T[];
   private index: number;
   private capacity: number;
diff --git a/packages/grafana-ui/src/components/Modal/ModalsContext.tsx b/packages/grafana-ui/src/components/Modal/ModalsContext.tsx
index 4a540716fee..734e3fe620b 100644
--- a/packages/grafana-ui/src/components/Modal/ModalsContext.tsx
+++ b/packages/grafana-ui/src/components/Modal/ModalsContext.tsx
@@ -17,10 +17,6 @@ export const ModalsContext = React.createContext<ModalsContextState>({
 
 interface ModalsProviderProps {
   children: React.ReactNode;
-  /** Set default component to render as modal. Useful when rendering modals from Angular */
-  component?: React.ComponentType<any> | null;
-  /** Set default component props. Useful when rendering modals from Angular */
-  props?: any;
 }
 
 /**
@@ -31,8 +27,8 @@ export class ModalsProvider extends Component<ModalsProviderProps, ModalsContext
   constructor(props: ModalsProviderProps) {
     super(props);
     this.state = {
-      component: props.component || null,
-      props: props.props || {},
+      component: null,
+      props: {},
       showModal: this.showModal,
       hideModal: this.hideModal,
     };
diff --git a/packages/grafana-ui/src/components/Select/SelectBase.tsx b/packages/grafana-ui/src/components/Select/SelectBase.tsx
index 0eb6a1fefeb..8609c307c25 100644
--- a/packages/grafana-ui/src/components/Select/SelectBase.tsx
+++ b/packages/grafana-ui/src/components/Select/SelectBase.tsx
@@ -195,9 +195,9 @@ export function SelectBase<T, Rest = {}>({
 
   const creatableProps: ComponentProps<typeof Creatable<SelectableValue<T>>> = {};
   let asyncSelectProps: any = {};
-  let selectedValue;
+  let selectedValue: any;
   if (isMulti && loadOptions) {
-    selectedValue = value as any;
+    selectedValue = value;
   } else {
     // If option is passed as a plain value (value property from SelectableValue property)
     // we are selecting the corresponding value from the options
diff --git a/packages/grafana-ui/src/components/Select/resetSelectStyles.ts b/packages/grafana-ui/src/components/Select/resetSelectStyles.ts
index 067cdaadf76..90ac3877c2a 100644
--- a/packages/grafana-ui/src/components/Select/resetSelectStyles.ts
+++ b/packages/grafana-ui/src/components/Select/resetSelectStyles.ts
@@ -51,7 +51,7 @@ export function useCustomSelectStyles(theme: GrafanaTheme2, width: number | stri
   return useMemo(() => {
     return {
       ...resetSelectStyles(theme),
-      menuPortal: (base: any) => {
+      menuPortal: (base: CSSObjectWithLabel) => {
         // Would like to correct top position when menu is placed bottom, but have props are not sent to this style function.
         // Only state is. https://github.com/JedWatson/react-select/blob/master/packages/react-select/src/components/Menu.tsx#L605
         return {
@@ -60,7 +60,7 @@ export function useCustomSelectStyles(theme: GrafanaTheme2, width: number | stri
         };
       },
       //These are required for the menu positioning to function
-      menu: ({ top, bottom, position }: any) => {
+      menu: ({ top, bottom, position }: CSSObjectWithLabel) => {
         return {
           top,
           bottom,
@@ -73,7 +73,7 @@ export function useCustomSelectStyles(theme: GrafanaTheme2, width: number | stri
         width: width ? theme.spacing(width) : '100%',
         display: width === 'auto' ? 'inline-flex' : 'flex',
       }),
-      option: (provided: any, state: any) => ({
+      option: (provided: CSSObjectWithLabel, state: any) => ({
         ...provided,
         opacity: state.isDisabled ? 0.5 : 1,
       }),
diff --git a/packages/grafana-ui/src/components/SingleStatShared/SingleStatBaseOptions.ts b/packages/grafana-ui/src/components/SingleStatShared/SingleStatBaseOptions.ts
index cf2dc4fffb0..b9aa005074c 100644
--- a/packages/grafana-ui/src/components/SingleStatShared/SingleStatBaseOptions.ts
+++ b/packages/grafana-ui/src/components/SingleStatShared/SingleStatBaseOptions.ts
@@ -197,7 +197,7 @@ export function sharedSingleStatMigrationHandler(panel: PanelModel<SingleStatBas
   }
 
   const previousVersion = parseFloat(panel.pluginVersion || '6.1');
-  let options = panel.options as any;
+  let options: any = panel.options;
 
   if (previousVersion < 6.2) {
     options = migrateFromValueOptions(options);
diff --git a/public/app/features/dashboard-scene/serialization/angularMigration.ts b/public/app/features/dashboard-scene/serialization/angularMigration.ts
index 606cf8545e4..81649cfadd3 100644
--- a/public/app/features/dashboard-scene/serialization/angularMigration.ts
+++ b/public/app/features/dashboard-scene/serialization/angularMigration.ts
@@ -5,7 +5,7 @@ import { autoMigrateAngular, PanelModel } from 'app/features/dashboard/state/Pan
 
 export function getAngularPanelMigrationHandler(oldModel: PanelModel) {
   return function handleAngularPanelMigrations(panel: PanelModelFromData, plugin: PanelPlugin) {
-    if (plugin.angularPanelCtrl) {
+    if ('angularPanelCtrl' in plugin && plugin.angularPanelCtrl) {
       panel.options = { angularOptions: oldModel.getOptionsToRemember() };
       return;
     }
diff --git a/public/app/features/dashboard/components/PanelEditor/state/actions.test.ts b/public/app/features/dashboard/components/PanelEditor/state/actions.test.ts
index 359e16f5159..1ee2e118ae5 100644
--- a/public/app/features/dashboard/components/PanelEditor/state/actions.test.ts
+++ b/public/app/features/dashboard/components/PanelEditor/state/actions.test.ts
@@ -139,7 +139,6 @@ describe('panelEditor actions', () => {
     it('should not increment configRev when no changes made and leaving panel edit', async () => {
       const sourcePanel = new PanelModel({ id: 12, type: 'graph' });
       sourcePanel.plugin = getPanelPlugin({});
-      sourcePanel.plugin.angularPanelCtrl = undefined;
 
       const dashboard = createDashboardModelFixture({
         panels: [{ id: 12, type: 'graph' }],
@@ -169,7 +168,6 @@ describe('panelEditor actions', () => {
     it('should apply changes when dashboard was saved from panel edit', async () => {
       const sourcePanel = new PanelModel({ id: 12, type: 'graph' });
       sourcePanel.plugin = getPanelPlugin({});
-      sourcePanel.plugin.angularPanelCtrl = undefined;
 
       const dashboard = createDashboardModelFixture({
         panels: [{ id: 12, type: 'graph' }],
diff --git a/public/app/features/search/service/frontend.ts b/public/app/features/search/service/frontend.ts
index b926d0c2cb2..40740144077 100644
--- a/public/app/features/search/service/frontend.ts
+++ b/public/app/features/search/service/frontend.ts
@@ -117,8 +117,7 @@ class FullResultCache {
     const allFields = this.full.dataFrame.fields;
     const haystack = this.names;
 
-    // eslint-disable-next-line
-    const values = allFields.map((v) => [] as any[]); // empty value for each field
+    const values = allFields.map<unknown[]>((v) => []); // empty value for each field
 
     let [idxs, info, order] = this.ufuzzy.search(haystack, query, 5);
 
diff --git a/public/app/plugins/panel/live/LiveChannelEditor.tsx b/public/app/plugins/panel/live/LiveChannelEditor.tsx
index 90cd5f4b474..06af567317e 100644
--- a/public/app/plugins/panel/live/LiveChannelEditor.tsx
+++ b/public/app/plugins/panel/live/LiveChannelEditor.tsx
@@ -135,7 +135,7 @@ export function LiveChannelEditor(props: Props) {
                 'Select watchable resource'
               )}
               onChange={(v) => {
-                const resource = (v as any).resource as GroupDiscoveryResource;
+                const resource: GroupDiscoveryResource = (v as any).resource;
                 if (resource) {
                   props.onChange({
                     scope: LiveChannelScope.Watch,