diff --git a/pkg/tsdb/opentsdb/opentsdb.go b/pkg/tsdb/opentsdb/opentsdb.go
index 533fadccb75..b621680bc82 100644
--- a/pkg/tsdb/opentsdb/opentsdb.go
+++ b/pkg/tsdb/opentsdb/opentsdb.go
@@ -3,10 +3,12 @@ package opentsdb
 import (
 	"context"
 	"encoding/json"
+	"errors"
 	"fmt"
 	"net/http"
 	"net/url"
 	"path"
+	"strings"
 
 	"github.com/grafana/grafana-plugin-sdk-go/backend"
 	"github.com/grafana/grafana-plugin-sdk-go/backend/datasource"
@@ -165,39 +167,58 @@ func (s *Service) QueryData(ctx context.Context, req *backend.QueryDataRequest)
 
 	dsInfo, err := s.getDSInfo(ctx, req.PluginContext)
 	if err != nil {
-		return nil, err
+		resp := backend.NewQueryDataResponse()
+		for _, q := range req.Queries {
+			resp.Responses[q.RefID] = backend.ErrorResponseWithErrorSource(backend.PluginError(err))
+		}
+		return resp, nil
 	}
 
 	result := backend.NewQueryDataResponse()
 
 	for _, query := range req.Queries {
+		metric, err := BuildMetric(query)
+		if err != nil {
+			result.Responses[query.RefID] = backend.ErrorResponseWithErrorSource(backend.PluginError(err))
+			continue
+		}
+
 		tsdbQuery := OpenTsdbQuery{
 			Start: query.TimeRange.From.Unix(),
 			End:   query.TimeRange.To.Unix(),
 			Queries: []map[string]any{
-				BuildMetric(query),
+				metric,
 			},
 		}
 
 		httpReq, err := CreateRequest(ctx, logger, dsInfo, tsdbQuery)
 		if err != nil {
-			return nil, err
+			var urlErr *url.Error
+			if errors.As(err, &urlErr) {
+				result.Responses[query.RefID] = backend.ErrorResponseWithErrorSource(backend.DownstreamError(err))
+			} else {
+				result.Responses[query.RefID] = backend.ErrorResponseWithErrorSource(backend.PluginError(err))
+			}
+			continue
 		}
 
 		httpRes, err := dsInfo.HTTPClient.Do(httpReq)
 		if err != nil {
-			return nil, err
-		}
-
-		defer func() {
-			if cerr := httpRes.Body.Close(); cerr != nil {
-				logger.Warn("failed to close response body", "error", cerr)
+			if backend.IsDownstreamHTTPError(err) {
+				err = backend.DownstreamError(err)
 			}
-		}()
+			var urlErr *url.Error
+			if errors.As(err, &urlErr) && urlErr.Err != nil && strings.HasPrefix(urlErr.Err.Error(), "unsupported protocol scheme") {
+				err = backend.DownstreamError(err)
+			}
+			result.Responses[query.RefID] = backend.ErrorResponseWithErrorSource(err)
+			continue
+		}
 
 		queryRes, err := ParseResponse(logger, httpRes, query.RefID, dsInfo.TSDBVersion)
 		if err != nil {
-			return nil, err
+			result.Responses[query.RefID] = backend.ErrorResponseWithErrorSource(backend.DownstreamError(err))
+			continue
 		}
 
 		result.Responses[query.RefID] = queryRes.Responses[query.RefID]
diff --git a/pkg/tsdb/opentsdb/opentsdb_test.go b/pkg/tsdb/opentsdb/opentsdb_test.go
index 72bbe6bf8b9..b194934df98 100644
--- a/pkg/tsdb/opentsdb/opentsdb_test.go
+++ b/pkg/tsdb/opentsdb/opentsdb_test.go
@@ -86,7 +86,7 @@ func TestBuildMetric(t *testing.T) {
 			Interval: 30 * time.Second,
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		require.Equal(t, "30s-avg", metric["downsample"], "should use query interval formatted as seconds")
 	})
 
@@ -104,7 +104,7 @@ func TestBuildMetric(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		require.Equal(t, "500ms-avg", metric["downsample"], "should convert 0.5s to 500ms")
 	})
 
@@ -123,7 +123,7 @@ func TestBuildMetric(t *testing.T) {
 			Interval: 500 * time.Millisecond,
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		require.Equal(t, "500ms-avg", metric["downsample"], "should use query interval formatted as milliseconds")
 	})
 
@@ -142,7 +142,7 @@ func TestBuildMetric(t *testing.T) {
 			Interval: 5 * time.Minute,
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		require.Equal(t, "5m-sum", metric["downsample"], "should use query interval formatted as minutes")
 	})
 
@@ -161,7 +161,7 @@ func TestBuildMetric(t *testing.T) {
 			Interval: 2 * time.Hour,
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		require.Equal(t, "2h-max", metric["downsample"], "should use query interval formatted as hours")
 	})
 
@@ -180,7 +180,7 @@ func TestBuildMetric(t *testing.T) {
 			Interval: 48 * time.Hour,
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		require.Equal(t, "2d-min", metric["downsample"], "should use query interval formatted as days")
 	})
 
@@ -199,7 +199,7 @@ func TestBuildMetric(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		require.True(t, metric["explicitTags"].(bool), "explicitTags should be true")
 
 		metricTags := metric["tags"].(map[string]any)
@@ -221,7 +221,7 @@ func TestBuildMetric(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		require.Nil(t, metric["explicitTags"], "explicitTags should not be present when false")
 	})
 }
@@ -501,7 +501,7 @@ func TestOpenTsdbExecutor(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 
 		require.Len(t, metric, 3)
 		require.Equal(t, "cpu.average.percent", metric["metric"])
@@ -523,7 +523,7 @@ func TestOpenTsdbExecutor(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 
 		require.Len(t, metric, 2)
 		require.Equal(t, "cpu.average.percent", metric["metric"])
@@ -544,7 +544,7 @@ func TestOpenTsdbExecutor(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 
 		require.Len(t, metric, 3)
 		require.Equal(t, "cpu.average.percent", metric["metric"])
@@ -570,7 +570,7 @@ func TestOpenTsdbExecutor(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 
 		require.Len(t, metric, 3)
 		require.Equal(t, "cpu.average.percent", metric["metric"])
@@ -601,7 +601,7 @@ func TestOpenTsdbExecutor(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 
 		require.Len(t, metric, 5)
 		require.Equal(t, "cpu.average.percent", metric["metric"])
@@ -636,7 +636,7 @@ func TestOpenTsdbExecutor(t *testing.T) {
 			),
 		}
 
-		metric := BuildMetric(query)
+		metric, _ := BuildMetric(query)
 		t.Log(metric)
 
 		require.Len(t, metric, 5)
diff --git a/pkg/tsdb/opentsdb/utils.go b/pkg/tsdb/opentsdb/utils.go
index df3ea67ae25..85cebb5a473 100644
--- a/pkg/tsdb/opentsdb/utils.go
+++ b/pkg/tsdb/opentsdb/utils.go
@@ -44,12 +44,12 @@ func FormatDownsampleInterval(ms int64) string {
 	return strconv.FormatInt(days, 10) + "d"
 }
 
-func BuildMetric(query backend.DataQuery) map[string]any {
+func BuildMetric(query backend.DataQuery) (map[string]any, error) {
 	metric := make(map[string]any)
 
 	var model QueryModel
 	if err := json.Unmarshal(query.JSON, &model); err != nil {
-		return nil
+		return nil, err
 	}
 
 	// Setting metric and aggregator
@@ -126,7 +126,7 @@ func BuildMetric(query backend.DataQuery) map[string]any {
 		metric["explicitTags"] = true
 	}
 
-	return metric
+	return metric, nil
 }
 
 func CreateRequest(ctx context.Context, logger log.Logger, dsInfo *datasourceInfo, data OpenTsdbQuery) (*http.Request, error) {