diff --git a/public/app/plugins/datasource/graphite/datasource.test.ts b/public/app/plugins/datasource/graphite/datasource.test.ts
index 849271524eb..a9268dbaed9 100644
--- a/public/app/plugins/datasource/graphite/datasource.test.ts
+++ b/public/app/plugins/datasource/graphite/datasource.test.ts
@@ -55,6 +55,10 @@ describe('graphiteDatasource', () => {
 
   describe('convertResponseToDataFrames', () => {
     it('should transform regular result', () => {
+      const refIDMap = {
+        refIDA: 'A',
+        refIDB: 'B',
+      };
       const result = ctx.ds.convertResponseToDataFrames(
         createFetchResponse({
           meta: {
@@ -65,7 +69,7 @@ describe('graphiteDatasource', () => {
           },
           series: [
             {
-              target: 'seriesA',
+              target: 'seriesA refIDA',
               datapoints: [
                 [100, 200],
                 [101, 201],
@@ -85,7 +89,7 @@ describe('graphiteDatasource', () => {
               ],
             },
             {
-              target: 'seriesB',
+              target: 'seriesB refIDB',
               meta: [
                 {
                   'aggnum-norm': 1,
@@ -105,7 +109,8 @@ describe('graphiteDatasource', () => {
               ],
             },
           ],
-        })
+        }),
+        refIDMap
       );
 
       expect(result.data.length).toBe(2);
@@ -113,24 +118,28 @@ describe('graphiteDatasource', () => {
       expect(getFrameDisplayName(result.data[1])).toBe('seriesB');
       expect(result.data[0].length).toBe(2);
       expect(result.data[0].meta.notices.length).toBe(1);
+      expect(result.data[0].refId).toBe('A');
       expect(result.data[0].meta.notices[0].text).toBe('Data is rolled up, aggregated over 2h using Average function');
       expect(result.data[1].meta.notices).toBeUndefined();
+      expect(result.data[1].refId).toBe('B');
     });
   });
 
   describe('When querying graphite with one target using query editor target spec', () => {
-    const query = {
-      panelId: 3,
-      dashboardId: 5,
-      range: { from: dateTime('2022-04-01T00:00:00'), to: dateTime('2022-07-01T00:00:00') },
-      targets: [{ target: 'prod1.count' }, { target: 'prod2.count' }],
-      maxDataPoints: 500,
-    };
-
     let response: unknown;
     let requestOptions: BackendSrvRequest;
 
     beforeEach(() => {
+      const query = {
+        panelId: 3,
+        dashboardId: 5,
+        range: { from: dateTime('2022-04-01T00:00:00'), to: dateTime('2022-07-01T00:00:00') },
+        targets: [
+          { target: 'prod1.count', refId: 'A' },
+          { target: 'prod2.count', refId: 'B' },
+        ],
+        maxDataPoints: 500,
+      };
       fetchMock.mockImplementation((options) => {
         requestOptions = options;
         return of(
@@ -164,8 +173,8 @@ describe('graphiteDatasource', () => {
 
     it('should query correctly', () => {
       const params = requestOptions.data.split('&');
-      expect(params).toContain('target=prod1.count');
-      expect(params).toContain('target=prod2.count');
+      expect(params).toContain(`target=${encodeURIComponent(`aliasSub(prod1.count, "(^.*$)", "\\1 A")`)}`);
+      expect(params).toContain(`target=${encodeURIComponent(`aliasSub(prod2.count, "(^.*$)", "\\1 B")`)}`);
       expect(params).toContain('from=1648789200');
       expect(params).toContain('until=1656655200');
     });
diff --git a/public/app/plugins/datasource/graphite/datasource.ts b/public/app/plugins/datasource/graphite/datasource.ts
index e3ab7e93dc7..23979d1d546 100644
--- a/public/app/plugins/datasource/graphite/datasource.ts
+++ b/public/app/plugins/datasource/graphite/datasource.ts
@@ -209,6 +209,17 @@ export class GraphiteDatasource
       return merge(...streams);
     }
 
+    // Use this object to map the original refID of the query to our sanitised one
+    const refIds: { [key: string]: string } = {};
+    for (const target of options.targets) {
+      // Sanitise the refID otherwise the Graphite query will fail
+      const formattedRefId = target.refId.replaceAll(' ', '_');
+      refIds[formattedRefId] = target.refId;
+      // Use aliasSub to include the refID in the response series name. This allows us to set the refID on the frame.
+      const updatedTarget = `aliasSub(${target.target}, "(^.*$)", "\\1 ${formattedRefId}")`;
+      target.target = updatedTarget;
+    }
+
     // handle the queries here
     const graphOptions = {
       from: this.translateTime(options.range.from, false, options.timezone),
@@ -243,7 +254,7 @@ export class GraphiteDatasource
       httpOptions.requestId = this.name + '.panelId.' + options.panelId;
     }
 
-    return this.doGraphiteRequest(httpOptions).pipe(map(this.convertResponseToDataFrames));
+    return this.doGraphiteRequest(httpOptions).pipe(map((result) => this.convertResponseToDataFrames(result, refIds)));
   }
 
   addTracingHeaders(
@@ -267,7 +278,7 @@ export class GraphiteDatasource
     }
   }
 
-  convertResponseToDataFrames = (result: FetchResponse): DataQueryResponse => {
+  convertResponseToDataFrames = (result: FetchResponse, refIdMap: { [key: string]: string }): DataQueryResponse => {
     const data: DataFrame[] = [];
     if (!result || !result.data) {
       return { data };
@@ -282,6 +293,9 @@ export class GraphiteDatasource
 
     for (let i = 0; i < series.length; i++) {
       const s = series[i];
+      // Retrieve the original refID of the query
+      const [target, refId] = s.target.split(' ');
+      s.target = target;
 
       // Disables Grafana own series naming
       s.title = s.target;
@@ -291,6 +305,8 @@ export class GraphiteDatasource
       }
 
       const frame = toDataFrame(s);
+      // Set the refID value on the frame
+      frame.refId = refIdMap[refId];
 
       // Metrictank metadata
       if (s.meta) {