diff --git a/pkg/tsdb/azuremonitor/metrics/azuremonitor-datasource.go b/pkg/tsdb/azuremonitor/metrics/azuremonitor-datasource.go
index 84279f4de67..9f256972543 100644
--- a/pkg/tsdb/azuremonitor/metrics/azuremonitor-datasource.go
+++ b/pkg/tsdb/azuremonitor/metrics/azuremonitor-datasource.go
@@ -368,6 +368,10 @@ func getQueryUrl(query *types.AzureMonitorQuery, azurePortalUrl string) (string,
 		return "", err
 	}
 	escapedChart := url.QueryEscape(string(chartDef))
+	// Azure Portal will timeout if the chart definition includes a space character encoded as '+'.
+	// url.QueryEscape encodes spaces as '+'.
+	// Note: this will not encode '+' literals as those are already encoded as '%2B' by url.QueryEscape
+	escapedChart = strings.ReplaceAll(escapedChart, "+", "%20")
 
 	return fmt.Sprintf("%s/#blade/Microsoft_Azure_MonitoringMetrics/Metrics.ReactView/Referer/MetricsExplorer/TimeContext/%s/ChartDefinition/%s", azurePortalUrl, escapedTime, escapedChart), nil
 }
diff --git a/pkg/tsdb/azuremonitor/metrics/azuremonitor-datasource_test.go b/pkg/tsdb/azuremonitor/metrics/azuremonitor-datasource_test.go
index 89faac286c0..abc44521375 100644
--- a/pkg/tsdb/azuremonitor/metrics/azuremonitor-datasource_test.go
+++ b/pkg/tsdb/azuremonitor/metrics/azuremonitor-datasource_test.go
@@ -188,7 +188,7 @@ func TestAzureMonitorBuildQueries(t *testing.T) {
 			expected := `http://ds/#blade/Microsoft_Azure_MonitoringMetrics/Metrics.ReactView/Referer/MetricsExplorer/` +
 				`TimeContext/%7B%22absolute%22%3A%7B%22startTime%22%3A%222018-03-15T13%3A00%3A00Z%22%2C%22endTime%22%3A%222018-03-15T13%3A34%3A00Z%22%7D%7D/` +
 				`ChartDefinition/%7B%22v2charts%22%3A%5B%7B%22metrics%22%3A%5B%7B%22resourceMetadata%22%3A%7B%22id%22%3A%22%2Fsubscriptions%2F12345678-aaaa-bbbb-cccc-123456789abc%2FresourceGroups%2Fgrafanastaging%2Fproviders%2FMicrosoft.Compute%2FvirtualMachines%2Fgrafana%22%7D%2C` +
-				`%22name%22%3A%22Percentage+CPU%22%2C%22aggregationType%22%3A4%2C%22namespace%22%3A%22Microsoft.Compute-virtualMachines%22%2C%22metricVisualization%22%3A%7B%22displayName%22%3A%22Percentage+CPU%22%2C%22resourceDisplayName%22%3A%22grafana%22%7D%7D%5D%7D%5D%7D`
+				`%22name%22%3A%22Percentage%20CPU%22%2C%22aggregationType%22%3A4%2C%22namespace%22%3A%22Microsoft.Compute-virtualMachines%22%2C%22metricVisualization%22%3A%7B%22displayName%22%3A%22Percentage%20CPU%22%2C%22resourceDisplayName%22%3A%22grafana%22%7D%7D%5D%7D%5D%7D`
 			actual, err := getQueryUrl(queries[0], "http://ds")
 			require.NoError(t, err)
 			require.Equal(t, expected, actual)