diff --git a/packages/grafana-runtime/src/index.ts b/packages/grafana-runtime/src/index.ts
index bc09e8a47f9..6e1104c92c2 100644
--- a/packages/grafana-runtime/src/index.ts
+++ b/packages/grafana-runtime/src/index.ts
@@ -28,7 +28,13 @@ export {
 export { PanelRenderer, type PanelRendererProps } from './components/PanelRenderer';
 export { PanelDataErrorView, type PanelDataErrorViewProps } from './components/PanelDataErrorView';
 export { toDataQueryError } from './utils/toDataQueryError';
-export { setQueryRunnerFactory, createQueryRunner, type QueryRunnerFactory } from './services/QueryRunner';
+export {
+  setQueryRunnerFactory,
+  createQueryRunner,
+  type QueryRunnerFactory,
+  setRunRequest,
+  getRunRequest,
+} from './services/QueryRunner';
 export { PluginPage } from './components/PluginPage';
 export type { PluginPageType, PluginPageProps } from './components/PluginPage';
 export {
diff --git a/packages/grafana-runtime/src/services/QueryRunner.ts b/packages/grafana-runtime/src/services/QueryRunner.ts
index 8ce5b100e7c..ce472067bfe 100644
--- a/packages/grafana-runtime/src/services/QueryRunner.ts
+++ b/packages/grafana-runtime/src/services/QueryRunner.ts
@@ -1,4 +1,6 @@
-import { QueryRunner } from '@grafana/data';
+import { Observable } from 'rxjs';
+
+import { DataQueryRequest, DataSourceApi, PanelData, QueryRunner } from '@grafana/data';
 
 let factory: QueryRunnerFactory | undefined;
 
@@ -31,3 +33,30 @@ export const createQueryRunner = (): QueryRunner => {
   }
   return factory();
 };
+
+type RunRequestFn = (
+  datasource: DataSourceApi,
+  request: DataQueryRequest,
+  queryFunction?: typeof datasource.query
+) => Observable<PanelData>;
+
+let runRequest: RunRequestFn | undefined;
+
+/**
+ * Used to exspose runRequest implementation to libraries, i.e. @grafana/scenes
+ *
+ * @internal
+ */
+export function setRunRequest(fn: RunRequestFn): void {
+  if (runRequest) {
+    throw new Error('runRequest function should only be set once, when Grafana is starting.');
+  }
+  runRequest = fn;
+}
+
+export function getRunRequest(): RunRequestFn {
+  if (!runRequest) {
+    throw new Error('getRunRequest can only be used after Grafana instance has started.');
+  }
+  return runRequest;
+}
diff --git a/public/app/app.ts b/public/app/app.ts
index cdf836281f2..1463dccfad7 100644
--- a/public/app/app.ts
+++ b/public/app/app.ts
@@ -31,6 +31,7 @@ import {
   setEchoSrv,
   setLocationSrv,
   setQueryRunnerFactory,
+  setRunRequest,
 } from '@grafana/runtime';
 import { setPanelDataErrorView } from '@grafana/runtime/src/components/PanelDataErrorView';
 import { setPanelRenderer } from '@grafana/runtime/src/components/PanelRenderer';
@@ -69,6 +70,7 @@ import { PanelRenderer } from './features/panel/components/PanelRenderer';
 import { DatasourceSrv } from './features/plugins/datasource_srv';
 import { preloadPlugins } from './features/plugins/pluginPreloader';
 import { QueryRunner } from './features/query/state/QueryRunner';
+import { runRequest } from './features/query/state/runRequest';
 import { initWindowRuntime } from './features/runtime/init';
 import { variableAdapters } from './features/variables/adapters';
 import { createAdHocVariableAdapter } from './features/variables/adhoc/adapter';
@@ -140,6 +142,9 @@ export class GrafanaApp {
       setQueryRunnerFactory(() => new QueryRunner());
       setVariableQueryRunner(new VariableQueryRunner());
 
+      // Provide runRequest implementation to packages, @grafana/scenes in particular
+      setRunRequest(runRequest);
+
       locationUtil.initialize({
         config,
         getTimeRangeForUrl: getTimeSrv().timeRangeForUrl,