diff --git a/public/app/plugins/datasource/loki/querybuilder/LokiQueryModeller.test.ts b/public/app/plugins/datasource/loki/querybuilder/LokiQueryModeller.test.ts
index 7c7b7ac23bc..1557d36249f 100644
--- a/public/app/plugins/datasource/loki/querybuilder/LokiQueryModeller.test.ts
+++ b/public/app/plugins/datasource/loki/querybuilder/LokiQueryModeller.test.ts
@@ -334,4 +334,15 @@ describe('LokiQueryModeller', () => {
       expect(result.operations[1].id).toBe(LokiOperationId.Unwrap);
     });
   });
+
+  describe('Disabled operations', () => {
+    it('Can query with line filter contains operation with empty params', () => {
+      expect(
+        modeller.renderQuery({
+          labels: [{ label: 'app', op: '=', value: 'grafana' }],
+          operations: [{ id: LokiOperationId.LineContains, params: [''], disabled: true }],
+        })
+      ).toBe('{app="grafana"}');
+    });
+  });
 });
diff --git a/public/app/plugins/datasource/loki/querybuilder/LokiQueryModeller.ts b/public/app/plugins/datasource/loki/querybuilder/LokiQueryModeller.ts
index 703d4c50f4f..ebb5aeefbb7 100644
--- a/public/app/plugins/datasource/loki/querybuilder/LokiQueryModeller.ts
+++ b/public/app/plugins/datasource/loki/querybuilder/LokiQueryModeller.ts
@@ -25,6 +25,9 @@ export class LokiQueryModeller extends QueryModellerBase {
 
   renderOperations(queryString: string, operations: QueryBuilderOperation[]): string {
     for (const operation of operations) {
+      if (operation.disabled) {
+        continue;
+      }
       const def = this.operationsRegistry.getIfExists(operation.id);
       if (!def) {
         console.error(`Could not find operation ${operation.id} in the registry`);
diff --git a/public/app/plugins/datasource/loki/querybuilder/binaryScalarOperations.ts b/public/app/plugins/datasource/loki/querybuilder/binaryScalarOperations.ts
index 3b2a56483ba..e41955641fd 100644
--- a/public/app/plugins/datasource/loki/querybuilder/binaryScalarOperations.ts
+++ b/public/app/plugins/datasource/loki/querybuilder/binaryScalarOperations.ts
@@ -95,6 +95,7 @@ export const binaryScalarOperations: QueryBuilderOperationDefinition[] = binaryS
     name: opDef.name,
     params,
     defaultParams,
+    toggleable: true,
     alternativesKey: 'binary scalar operations',
     category: LokiVisualQueryOperationCategory.BinaryOps,
     renderer: getSimpleBinaryRenderer(opDef.sign),
diff --git a/public/app/plugins/datasource/loki/querybuilder/components/LokiQueryBuilder.test.tsx b/public/app/plugins/datasource/loki/querybuilder/components/LokiQueryBuilder.test.tsx
index 2fa9d9f1801..137d733b7bf 100644
--- a/public/app/plugins/datasource/loki/querybuilder/components/LokiQueryBuilder.test.tsx
+++ b/public/app/plugins/datasource/loki/querybuilder/components/LokiQueryBuilder.test.tsx
@@ -7,7 +7,7 @@ import { config } from '@grafana/runtime';
 import { createLokiDatasource } from '../../__mocks__/datasource';
 import { LokiOperationId, LokiVisualQuery } from '../types';
 
-import { LokiQueryBuilder, TIME_SPAN_TO_TRIGGER_SAMPLES } from './LokiQueryBuilder';
+import { LokiQueryBuilder, Props, TIME_SPAN_TO_TRIGGER_SAMPLES } from './LokiQueryBuilder';
 import { EXPLAIN_LABEL_FILTER_CONTENT } from './LokiQueryBuilderExplained';
 
 const MISSING_LABEL_FILTER_ERROR_MESSAGE = 'Select at least 1 label filter (label and value)';
@@ -317,6 +317,68 @@ describe('LokiQueryBuilder', () => {
       expect(props.datasource.getDataSamples).toHaveBeenCalledTimes(1);
     });
   });
+
+  describe('Disabling operations', () => {
+    let props: Omit<Props, 'query'>;
+    beforeEach(() => {
+      props = createDefaultProps();
+      props.datasource.getDataSamples = jest.fn().mockReturnValue(new Promise(() => {}));
+      props.datasource.languageProvider.fetchLabelValues = jest.fn().mockReturnValue(['a', 'b']);
+    });
+    it('Allows to disable operations', async () => {
+      const onChange = jest.fn();
+
+      const query: LokiVisualQuery = {
+        labels: [{ op: '=', label: 'job', value: 'grafana' }],
+        operations: [
+          {
+            id: LokiOperationId.Logfmt,
+            params: [],
+          },
+        ],
+      };
+      render(<LokiQueryBuilder {...props} onChange={onChange} query={query} />);
+
+      expect(screen.getByText('Logfmt')).toBeInTheDocument();
+      await userEvent.click(screen.getByTitle('Disable operation'));
+      expect(onChange).toHaveBeenCalledWith({
+        ...query,
+        operations: [
+          {
+            ...query.operations[0],
+            disabled: true,
+          },
+        ],
+      });
+    });
+
+    it('Allows to enable operations', async () => {
+      const onChange = jest.fn();
+      const query: LokiVisualQuery = {
+        labels: [{ op: '=', label: 'job', value: 'grafana' }],
+        operations: [
+          {
+            id: LokiOperationId.Logfmt,
+            params: [],
+            disabled: true,
+          },
+        ],
+      };
+      render(<LokiQueryBuilder {...props} onChange={onChange} query={query} />);
+
+      expect(screen.getByText('Logfmt')).toBeInTheDocument();
+      await userEvent.click(screen.getByTitle('Enable operation'));
+      expect(onChange).toHaveBeenCalledWith({
+        ...query,
+        operations: [
+          {
+            ...query.operations[0],
+            disabled: false,
+          },
+        ],
+      });
+    });
+  });
 });
 
 const getSelectParent = (input: HTMLElement) =>
diff --git a/public/app/plugins/datasource/loki/querybuilder/operationUtils.ts b/public/app/plugins/datasource/loki/querybuilder/operationUtils.ts
index 971ae7e3fc0..2ac580b9dc3 100644
--- a/public/app/plugins/datasource/loki/querybuilder/operationUtils.ts
+++ b/public/app/plugins/datasource/loki/querybuilder/operationUtils.ts
@@ -48,6 +48,7 @@ export function createRangeOperation(
     name: getLokiOperationDisplayName(name),
     params: params,
     defaultParams,
+    toggleable: true,
     alternativesKey: 'range function',
     category: LokiVisualQueryOperationCategory.RangeFunctions,
     orderRank: LokiOperationOrder.RangeVectorFunction,
@@ -86,6 +87,7 @@ export function createRangeOperationWithGrouping(name: string): QueryBuilderOper
         },
       ],
       defaultParams: [...rangeOperation.defaultParams, ''],
+      toggleable: true,
       alternativesKey: 'range function with grouping',
       category: LokiVisualQueryOperationCategory.RangeFunctions,
       renderer: getRangeAggregationWithGroupingRenderer(name, 'by'),
@@ -431,6 +433,7 @@ export function createAggregationOperation(
         },
       ],
       defaultParams: [],
+      toggleable: true,
       alternativesKey: 'plain aggregations',
       category: LokiVisualQueryOperationCategory.Aggregations,
       renderer: functionRendererLeft,
diff --git a/public/app/plugins/datasource/loki/querybuilder/operations.ts b/public/app/plugins/datasource/loki/querybuilder/operations.ts
index 1ecdec52d9e..5fb91ce0f2f 100644
--- a/public/app/plugins/datasource/loki/querybuilder/operations.ts
+++ b/public/app/plugins/datasource/loki/querybuilder/operations.ts
@@ -87,6 +87,7 @@ function getOperationDefinitions(): QueryBuilderOperationDefinition[] {
         },
       ],
       defaultParams: [],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.Parsers,
@@ -125,6 +126,7 @@ function getOperationDefinitions(): QueryBuilderOperationDefinition[] {
         },
       ],
       defaultParams: [false, false],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.Parsers,
@@ -147,6 +149,7 @@ function getOperationDefinitions(): QueryBuilderOperationDefinition[] {
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.Parsers,
@@ -169,6 +172,7 @@ function getOperationDefinitions(): QueryBuilderOperationDefinition[] {
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.Parsers,
@@ -182,6 +186,7 @@ function getOperationDefinitions(): QueryBuilderOperationDefinition[] {
       name: 'Unpack',
       params: [],
       defaultParams: [],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.Parsers,
@@ -204,6 +209,7 @@ function getOperationDefinitions(): QueryBuilderOperationDefinition[] {
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.PipeOperations,
@@ -225,6 +231,7 @@ Example: \`{{.status_code}} - {{.message}}\`
         { name: 'Rename to', type: 'string' },
       ],
       defaultParams: ['', ''],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.PipeOperations,
@@ -255,6 +262,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'line filter',
       category: LokiVisualQueryOperationCategory.LineFilters,
       orderRank: LokiOperationOrder.LineFilters,
@@ -278,6 +286,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'line filter',
       category: LokiVisualQueryOperationCategory.LineFilters,
       orderRank: LokiOperationOrder.LineFilters,
@@ -301,6 +310,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'line filter',
       category: LokiVisualQueryOperationCategory.LineFilters,
       orderRank: LokiOperationOrder.LineFilters,
@@ -324,6 +334,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'line filter',
       category: LokiVisualQueryOperationCategory.LineFilters,
       orderRank: LokiOperationOrder.LineFilters,
@@ -347,6 +358,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'line filter',
       category: LokiVisualQueryOperationCategory.LineFilters,
       orderRank: LokiOperationOrder.LineFilters,
@@ -370,6 +382,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'line filter',
       category: LokiVisualQueryOperationCategory.LineFilters,
       orderRank: LokiOperationOrder.LineFilters,
@@ -397,6 +410,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: ['|=', ''],
+      toggleable: true,
       alternativesKey: 'line filter',
       category: LokiVisualQueryOperationCategory.LineFilters,
       orderRank: LokiOperationOrder.LineFilters,
@@ -427,6 +441,7 @@ Example: \`\`error_level=\`level\` \`\`
         { name: 'Value', type: 'string', minWidth: 14 },
       ],
       defaultParams: ['', '=', ''],
+      toggleable: true,
       alternativesKey: 'label filter',
       category: LokiVisualQueryOperationCategory.LabelFilters,
       orderRank: LokiOperationOrder.PipeOperations,
@@ -448,6 +463,7 @@ Example: \`\`error_level=\`level\` \`\`
         { name: 'Value', type: 'string', minWidth: 14 },
       ],
       defaultParams: ['', '=', ''],
+      toggleable: true,
       alternativesKey: 'label filter',
       category: LokiVisualQueryOperationCategory.LabelFilters,
       orderRank: LokiOperationOrder.PipeOperations,
@@ -461,6 +477,7 @@ Example: \`\`error_level=\`level\` \`\`
       name: 'No pipeline errors',
       params: [],
       defaultParams: [],
+      toggleable: true,
       alternativesKey: 'label filter',
       category: LokiVisualQueryOperationCategory.LabelFilters,
       orderRank: LokiOperationOrder.NoErrors,
@@ -489,6 +506,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: ['', ''],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.Unwrap,
@@ -509,6 +527,7 @@ Example: \`\`error_level=\`level\` \`\`
       name: 'Decolorize',
       params: [],
       defaultParams: [],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.PipeOperations,
@@ -533,6 +552,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.PipeOperations,
@@ -557,6 +577,7 @@ Example: \`\`error_level=\`level\` \`\`
         },
       ],
       defaultParams: [''],
+      toggleable: true,
       alternativesKey: 'format',
       category: LokiVisualQueryOperationCategory.Formats,
       orderRank: LokiOperationOrder.PipeOperations,
@@ -571,6 +592,7 @@ Example: \`\`error_level=\`level\` \`\`
       name: 'Binary operation with query',
       params: [],
       defaultParams: [],
+      toggleable: true,
       category: LokiVisualQueryOperationCategory.BinaryOps,
       renderer: (model, def, innerExpr) => innerExpr,
       addOperationHandler: addNestedQueryHandler,