diff --git a/public/app/features/dashboard-scene/panel-edit/PanelDataPane/PanelDataQueriesTab.test.tsx b/public/app/features/dashboard-scene/panel-edit/PanelDataPane/PanelDataQueriesTab.test.tsx
index 3fa7b13563c..fe807ace5b2 100644
--- a/public/app/features/dashboard-scene/panel-edit/PanelDataPane/PanelDataQueriesTab.test.tsx
+++ b/public/app/features/dashboard-scene/panel-edit/PanelDataPane/PanelDataQueriesTab.test.tsx
@@ -520,6 +520,27 @@ describe('PanelDataQueriesTab', () => {
           });
           expect(dataObj.state.minInterval).toBe('1s');
         });
+
+        it('should update min interval to undefined if empty input', async () => {
+          const { queriesTab } = await setupScene('panel-1');
+          const dataObj = queriesTab.queryRunner;
+
+          expect(dataObj.state.maxDataPoints).toBeUndefined();
+
+          queriesTab.onQueryOptionsChange({
+            dataSource: { name: 'grafana-testdata', type: 'grafana-testdata-datasource', default: true },
+            queries: [],
+            minInterval: '1s',
+          });
+          expect(dataObj.state.minInterval).toBe('1s');
+
+          queriesTab.onQueryOptionsChange({
+            dataSource: { name: 'grafana-testdata', type: 'grafana-testdata-datasource', default: true },
+            queries: [],
+            minInterval: null,
+          });
+          expect(dataObj.state.minInterval).toBe(undefined);
+        });
       });
 
       describe('query caching', () => {
diff --git a/public/app/features/dashboard-scene/panel-edit/PanelDataPane/PanelDataQueriesTab.tsx b/public/app/features/dashboard-scene/panel-edit/PanelDataPane/PanelDataQueriesTab.tsx
index 9eb246042fd..9881cca477e 100644
--- a/public/app/features/dashboard-scene/panel-edit/PanelDataPane/PanelDataQueriesTab.tsx
+++ b/public/app/features/dashboard-scene/panel-edit/PanelDataPane/PanelDataQueriesTab.tsx
@@ -201,8 +201,8 @@ export class PanelDataQueriesTab extends SceneObjectBase<PanelDataQueriesTabStat
       dataObjStateUpdate.maxDataPoints = options.maxDataPoints ?? undefined;
     }
 
-    if (options.minInterval !== dataObj.state.minInterval && options.minInterval !== null) {
-      dataObjStateUpdate.minInterval = options.minInterval;
+    if (options.minInterval !== dataObj.state.minInterval) {
+      dataObjStateUpdate.minInterval = options.minInterval ?? undefined;
     }
 
     const timeFrom = options.timeRange?.from ?? undefined;