diff --git a/public/app/features/alerting/unified/AmRoutes.test.tsx b/public/app/features/alerting/unified/AmRoutes.test.tsx
index 247fe95ab64..819823f6756 100644
--- a/public/app/features/alerting/unified/AmRoutes.test.tsx
+++ b/public/app/features/alerting/unified/AmRoutes.test.tsx
@@ -95,6 +95,9 @@ const ui = {
   groupWaitContainer: byTestId('am-group-wait'),
   groupIntervalContainer: byTestId('am-group-interval'),
   groupRepeatContainer: byTestId('am-repeat-interval'),
+
+  confirmDeleteModal: byRole('dialog'),
+  confirmDeleteButton: byLabelText('Confirm Modal Danger Button'),
 };
 
 describe('AmRoutes', () => {
@@ -154,6 +157,8 @@ describe('AmRoutes', () => {
     },
   ];
 
+  const emptyRoute: Route = {};
+
   const simpleRoute: Route = {
     receiver: 'simple-receiver',
     matchers: ['hello=world', 'foo!=bar'],
@@ -465,6 +470,61 @@ describe('AmRoutes', () => {
     });
   });
 
+  it('Should be able to delete an empty route', async () => {
+    const routeConfig = {
+      continue: false,
+      receiver: 'default',
+      group_by: ['alertname'],
+      routes: [emptyRoute],
+      group_interval: '4m',
+      group_wait: '1m',
+      repeat_interval: '5h',
+      mute_time_intervals: [],
+    };
+
+    const defaultConfig: AlertManagerCortexConfig = {
+      alertmanager_config: {
+        receivers: [{ name: 'default' }, { name: 'critical' }],
+        route: routeConfig,
+        templates: [],
+      },
+      template_files: {},
+    };
+
+    mocks.api.fetchAlertManagerConfig.mockImplementation(() => {
+      return Promise.resolve(defaultConfig);
+    });
+
+    mocks.api.updateAlertManagerConfig.mockResolvedValue(Promise.resolve());
+
+    await renderAmRoutes(GRAFANA_RULES_SOURCE_NAME);
+    expect(mocks.api.fetchAlertManagerConfig).toHaveBeenCalled();
+
+    const deleteButtons = await ui.deleteRouteButton.findAll();
+    expect(deleteButtons).toHaveLength(1);
+
+    await userEvent.click(deleteButtons[0]);
+
+    const confirmDeleteButton = ui.confirmDeleteButton.get(ui.confirmDeleteModal.get());
+    expect(confirmDeleteButton).toBeInTheDocument();
+
+    await userEvent.click(confirmDeleteButton);
+
+    expect(mocks.api.updateAlertManagerConfig).toHaveBeenCalledWith<[string, AlertManagerCortexConfig]>(
+      GRAFANA_RULES_SOURCE_NAME,
+      {
+        ...defaultConfig,
+        alertmanager_config: {
+          ...defaultConfig.alertmanager_config,
+          route: {
+            ...routeConfig,
+            routes: [],
+          },
+        },
+      }
+    );
+  });
+
   it('Keeps matchers for non-grafana alertmanager sources', async () => {
     const defaultConfig: AlertManagerCortexConfig = {
       alertmanager_config: {
diff --git a/public/app/features/alerting/unified/utils/amroutes.ts b/public/app/features/alerting/unified/utils/amroutes.ts
index 7d5a2bb8e6e..18f804aae39 100644
--- a/public/app/features/alerting/unified/utils/amroutes.ts
+++ b/public/app/features/alerting/unified/utils/amroutes.ts
@@ -77,20 +77,22 @@ export const emptyRoute: FormAmRoute = {
   muteTimeIntervals: [],
 };
 
-//returns route, and a record mapping id to existing route route
+//returns route, and a record mapping id to existing route
 export const amRouteToFormAmRoute = (route: Route | undefined): [FormAmRoute, Record<string, Route>] => {
-  if (!route || Object.keys(route).length === 0) {
+  if (!route) {
     return [emptyRoute, {}];
   }
 
-  const [groupWaitValue, groupWaitValueType] = intervalToValueAndType(route.group_wait, ['', 's']);
-  const [groupIntervalValue, groupIntervalValueType] = intervalToValueAndType(route.group_interval, ['', 'm']);
-  const [repeatIntervalValue, repeatIntervalValueType] = intervalToValueAndType(route.repeat_interval, ['', 'h']);
-
   const id = String(Math.random());
   const id2route = {
     [id]: route,
   };
+
+  if (Object.keys(route).length === 0) {
+    const formAmRoute = { ...emptyRoute, id };
+    return [formAmRoute, id2route];
+  }
+
   const formRoutes: FormAmRoute[] = [];
   route.routes?.forEach((subRoute) => {
     const [subFormRoute, subId2Route] = amRouteToFormAmRoute(subRoute);
@@ -105,6 +107,10 @@ export const amRouteToFormAmRoute = (route: Route | undefined): [FormAmRoute, Re
         (matcher) => ({ name: matcher[0], operator: matcher[1], value: matcher[2] } as MatcherFieldValue)
       ) ?? [];
 
+  const [groupWaitValue, groupWaitValueType] = intervalToValueAndType(route.group_wait, ['', 's']);
+  const [groupIntervalValue, groupIntervalValueType] = intervalToValueAndType(route.group_interval, ['', 'm']);
+  const [repeatIntervalValue, repeatIntervalValueType] = intervalToValueAndType(route.repeat_interval, ['', 'h']);
+
   return [
     {
       id,