diff --git a/public/app/features/alerting/unified/RuleEditorGrafanaRules.test.tsx b/public/app/features/alerting/unified/RuleEditorGrafanaRules.test.tsx
index 8545ea4f1d6..b76654076cf 100644
--- a/public/app/features/alerting/unified/RuleEditorGrafanaRules.test.tsx
+++ b/public/app/features/alerting/unified/RuleEditorGrafanaRules.test.tsx
@@ -1,7 +1,6 @@
 import 'whatwg-fetch';
 import { screen, waitFor, waitForElementToBeRemoved, within } from '@testing-library/react';
 import userEvent, { PointerEventsCheckLevel } from '@testing-library/user-event';
-import { setupServer } from 'msw/node';
 import React from 'react';
 import { renderRuleEditor, ui } from 'test/helpers/alertingRuleEditor';
 import { clickSelectOption } from 'test/helpers/selectOptionInTest';
@@ -9,7 +8,11 @@ import { byRole } from 'testing-library-selector';
 
 import { setDataSourceSrv } from '@grafana/runtime';
 import { contextSrv } from 'app/core/services/context_srv';
-import { mockApi } from 'app/features/alerting/unified/mockApi';
+import { mockApi, setupMswServer } from 'app/features/alerting/unified/mockApi';
+import {
+  defaultAlertmanagerChoiceResponse,
+  mockAlertmanagerChoiceResponse,
+} from 'app/features/alerting/unified/mocks/alertmanagerApi';
 import { DashboardSearchHit, DashboardSearchItemType } from 'app/features/search/types';
 import { AccessControlAction } from 'app/types';
 import { GrafanaAlertStateDecision, PromApplication } from 'app/types/unified-alerting-dto';
@@ -64,13 +67,13 @@ const mocks = {
   },
 };
 
-const server = setupServer();
+const server = setupMswServer();
 
 const getLabelInput = (selector: HTMLElement) => within(selector).getByRole('combobox');
 describe('RuleEditor grafana managed rules', () => {
   beforeEach(() => {
     mockApi(server).eval({ results: {} });
-    server.listen();
+    mockAlertmanagerChoiceResponse(server, defaultAlertmanagerChoiceResponse);
     jest.clearAllMocks();
     contextSrv.isEditor = true;
     contextSrv.hasEditPermissionInFolders = true;
@@ -89,14 +92,6 @@ describe('RuleEditor grafana managed rules', () => {
     ]);
   });
 
-  afterEach(() => {
-    server.resetHandlers();
-  });
-
-  afterAll(() => {
-    server.close();
-  });
-
   it('can create new grafana managed alert', async () => {
     const dataSources = {
       default: mockDataSource(
diff --git a/public/app/features/alerting/unified/RuleEditorRecordingRule.test.tsx b/public/app/features/alerting/unified/RuleEditorRecordingRule.test.tsx
index 806bc82c75d..b09d022eb3f 100644
--- a/public/app/features/alerting/unified/RuleEditorRecordingRule.test.tsx
+++ b/public/app/features/alerting/unified/RuleEditorRecordingRule.test.tsx
@@ -1,7 +1,6 @@
 import 'whatwg-fetch';
 import { screen, waitFor, waitForElementToBeRemoved, within } from '@testing-library/react';
 import userEvent, { PointerEventsCheckLevel } from '@testing-library/user-event';
-import { setupServer } from 'msw/node';
 import React from 'react';
 import { renderRuleEditor, ui } from 'test/helpers/alertingRuleEditor';
 import { clickSelectOption } from 'test/helpers/selectOptionInTest';
@@ -9,7 +8,7 @@ import { byText } from 'testing-library-selector';
 
 import { setDataSourceSrv } from '@grafana/runtime';
 import { contextSrv } from 'app/core/services/context_srv';
-import { mockApi } from 'app/features/alerting/unified/mockApi';
+import { mockApi, setupMswServer } from 'app/features/alerting/unified/mockApi';
 import { AccessControlAction } from 'app/types';
 import { PromApplication } from 'app/types/unified-alerting-dto';
 
@@ -96,12 +95,11 @@ const mocks = {
 
 const getLabelInput = (selector: HTMLElement) => within(selector).getByRole('combobox');
 
-const server = setupServer();
+const server = setupMswServer();
 
 describe('RuleEditor recording rules', () => {
   beforeEach(() => {
     mockApi(server).eval({ results: {} });
-    server.listen();
     jest.clearAllMocks();
     contextSrv.isEditor = true;
     contextSrv.hasEditPermissionInFolders = true;
@@ -120,14 +118,6 @@ describe('RuleEditor recording rules', () => {
     ]);
   });
 
-  afterEach(() => {
-    server.resetHandlers();
-  });
-
-  afterAll(() => {
-    server.close();
-  });
-
   it('can create a new cloud recording rule', async () => {
     setDataSourceSrv(new MockDataSourceSrv(dataSources));
     mocks.getAllDataSources.mockReturnValue(Object.values(dataSources));
diff --git a/public/app/features/alerting/unified/components/rule-editor/alert-rule-form/simplifiedRouting/SimplifiedRuleEditor.test.tsx b/public/app/features/alerting/unified/components/rule-editor/alert-rule-form/simplifiedRouting/SimplifiedRuleEditor.test.tsx
index 5ac83f63d87..1ae84f9f1d6 100644
--- a/public/app/features/alerting/unified/components/rule-editor/alert-rule-form/simplifiedRouting/SimplifiedRuleEditor.test.tsx
+++ b/public/app/features/alerting/unified/components/rule-editor/alert-rule-form/simplifiedRouting/SimplifiedRuleEditor.test.tsx
@@ -1,7 +1,6 @@
 import 'whatwg-fetch';
 import { render, screen, waitFor, waitForElementToBeRemoved } from '@testing-library/react';
 import userEvent from '@testing-library/user-event';
-import { setupServer } from 'msw/node';
 import React from 'react';
 import { Route } from 'react-router-dom';
 import { TestProvider } from 'test/helpers/TestProvider';
@@ -21,7 +20,7 @@ import {
 } from 'app/features/alerting/unified/api/ruler';
 import * as useContactPoints from 'app/features/alerting/unified/components/contact-points/useContactPoints';
 import * as dsByPermission from 'app/features/alerting/unified/hooks/useAlertManagerSources';
-import { mockApi } from 'app/features/alerting/unified/mockApi';
+import { mockApi, setupMswServer } from 'app/features/alerting/unified/mockApi';
 import { MockDataSourceSrv, grantUserPermissions, mockDataSource } from 'app/features/alerting/unified/mocks';
 import { AlertmanagerProvider } from 'app/features/alerting/unified/state/AlertmanagerContext';
 import { fetchRulerRulesIfNotFetchedYet } from 'app/features/alerting/unified/state/actions';
@@ -105,12 +104,11 @@ const mocks = {
   },
 };
 
-const server = setupServer();
+const server = setupMswServer();
 
 describe('Can create a new grafana managed alert unsing simplified routing', () => {
   beforeEach(() => {
     mockApi(server).eval({ results: {} });
-    server.listen();
     jest.clearAllMocks();
     contextSrv.isEditor = true;
     contextSrv.hasEditPermissionInFolders = true;
@@ -142,14 +140,6 @@ describe('Can create a new grafana managed alert unsing simplified routing', ()
     });
   });
 
-  afterEach(() => {
-    server.resetHandlers();
-  });
-
-  afterAll(() => {
-    server.close();
-  });
-
   const dataSources = {
     default: mockDataSource(
       {
diff --git a/public/app/features/alerting/unified/components/rules/RulesFilter.test.tsx b/public/app/features/alerting/unified/components/rules/RulesFilter.test.tsx
index dcadfb9d858..eeb0791da31 100644
--- a/public/app/features/alerting/unified/components/rules/RulesFilter.test.tsx
+++ b/public/app/features/alerting/unified/components/rules/RulesFilter.test.tsx
@@ -1,20 +1,19 @@
 import 'whatwg-fetch';
 import { render, screen } from '@testing-library/react';
 import userEvent from '@testing-library/user-event';
-import { setupServer } from 'msw/node';
 import React from 'react';
 import { TestProvider } from 'test/helpers/TestProvider';
 import { byLabelText, byRole } from 'testing-library-selector';
 
 import { locationService, setDataSourceSrv } from '@grafana/runtime';
-import { mockSearchApi } from 'app/features/alerting/unified/mockApi';
+import { mockSearchApi, setupMswServer } from 'app/features/alerting/unified/mockApi';
 
 import * as analytics from '../../Analytics';
 import { MockDataSourceSrv } from '../../mocks';
 
 import RulesFilter from './RulesFilter';
 
-const server = setupServer();
+const server = setupMswServer();
 jest.spyOn(analytics, 'logInfo');
 
 jest.mock('./MultipleDataSourcePicker', () => {
@@ -44,15 +43,6 @@ const ui = {
 beforeEach(() => {
   locationService.replace({ search: '' });
   mockSearchApi(server).search([]);
-  server.listen({ onUnhandledRequest: 'error' });
-});
-
-afterEach(() => {
-  server.resetHandlers();
-});
-
-afterAll(() => {
-  server.close();
 });
 
 describe('RulesFilter', () => {
diff --git a/public/app/features/alerting/unified/hooks/useAbilities.test.tsx b/public/app/features/alerting/unified/hooks/useAbilities.test.tsx
index 935708701b2..0a626fdd737 100644
--- a/public/app/features/alerting/unified/hooks/useAbilities.test.tsx
+++ b/public/app/features/alerting/unified/hooks/useAbilities.test.tsx
@@ -6,7 +6,11 @@ import React, { PropsWithChildren } from 'react';
 import { Router } from 'react-router-dom';
 import { TestProvider } from 'test/helpers/TestProvider';
 
-import { mockFolderApi } from 'app/features/alerting/unified/mockApi';
+import { mockFolderApi, setupMswServer } from 'app/features/alerting/unified/mockApi';
+import {
+  defaultAlertmanagerChoiceResponse,
+  mockAlertmanagerChoiceResponse,
+} from 'app/features/alerting/unified/mocks/alertmanagerApi';
 import { AlertManagerDataSourceJsonData, AlertManagerImplementation } from 'app/plugins/datasource/alertmanager/types';
 import { AccessControlAction } from 'app/types';
 import { RulerGrafanaRuleDTO } from 'app/types/unified-alerting-dto';
@@ -141,17 +145,18 @@ describe('alertmanager abilities', () => {
 });
 
 describe('AlertRule abilities', () => {
+  const server = setupMswServer();
   it('should report that all actions are supported for a Grafana Managed alert rule', async () => {
     const rule = getGrafanaRule();
 
     // TODO: Remove server mocking within test once server is run before all tests
-    const server = setupServer();
     mockFolderApi(server).folder(
       (rule.rulerRule as RulerGrafanaRuleDTO).grafana_alert.namespace_uid,
       mockFolder({
         accessControl: { [AccessControlAction.AlertingRuleUpdate]: false },
       })
     );
+    mockAlertmanagerChoiceResponse(server, defaultAlertmanagerChoiceResponse);
     server.listen();
 
     const abilities = renderHook(() => useAllAlertRuleAbilities(rule), { wrapper: TestProvider });
@@ -165,8 +170,6 @@ describe('AlertRule abilities', () => {
     });
 
     expect(abilities.result.current).toMatchSnapshot();
-
-    server.close();
   });
 
   it('should report no permissions while we are loading data for cloud rule', async () => {