diff --git a/eslint-suppressions.json b/eslint-suppressions.json
index 8d4775e9a30..91901fdad41 100644
--- a/eslint-suppressions.json
+++ b/eslint-suppressions.json
@@ -4108,7 +4108,7 @@
       "count": 4
     },
     "@typescript-eslint/no-explicit-any": {
-      "count": 10
+      "count": 8
     }
   },
   "public/app/plugins/datasource/graphite/gfunc.ts": {
diff --git a/pkg/tsdb/graphite/graphite.go b/pkg/tsdb/graphite/graphite.go
index 62b932763af..512598da1b7 100644
--- a/pkg/tsdb/graphite/graphite.go
+++ b/pkg/tsdb/graphite/graphite.go
@@ -109,8 +109,10 @@ func (s *Service) createRequest(ctx context.Context, dsInfo *datasourceInfo, par
 
 	if params.QueryParams != nil {
 		queryValues := u.Query()
-		for k, v := range params.QueryParams {
-			queryValues.Set(k, v)
+		for key, values := range params.QueryParams {
+			for _, value := range values {
+				queryValues.Add(key, value)
+			}
 		}
 		u.RawQuery = queryValues.Encode()
 	}
diff --git a/pkg/tsdb/graphite/graphite_test.go b/pkg/tsdb/graphite/graphite_test.go
index bff49068f30..9234c6bf4a3 100644
--- a/pkg/tsdb/graphite/graphite_test.go
+++ b/pkg/tsdb/graphite/graphite_test.go
@@ -26,7 +26,7 @@ func Test_CreateRequest(t *testing.T) {
 		expectedMethod string
 		expectedError  string
 		checkHeaders   map[string]string
-		checkQuery     map[string]string
+		checkQuery     map[string][]string
 	}{
 		{
 			name:           "basic request with default GET method",
@@ -57,16 +57,16 @@ func Test_CreateRequest(t *testing.T) {
 			name:   "request with query parameters",
 			dsInfo: dsInfo,
 			params: URLParams{
-				QueryParams: map[string]string{
-					"query":  "stats.counters.*",
-					"format": "json",
+				QueryParams: map[string][]string{
+					"query":  {"stats.counters.*"},
+					"format": {"json"},
 				},
 			},
 			expectedURL:    "http://graphite.example.com",
 			expectedMethod: "GET",
-			checkQuery: map[string]string{
-				"query":  "stats.counters.*",
-				"format": "json",
+			checkQuery: map[string][]string{
+				"query":  {"stats.counters.*"},
+				"format": {"json"},
 			},
 		},
 		{
@@ -99,9 +99,9 @@ func Test_CreateRequest(t *testing.T) {
 			params: URLParams{
 				SubPath: "/metrics/expand",
 				Method:  "POST",
-				QueryParams: map[string]string{
-					"groupByExpr": "true",
-					"leavesOnly":  "false",
+				QueryParams: map[string][]string{
+					"groupByExpr": {"true"},
+					"leavesOnly":  {"false"},
 				},
 				Headers: map[string]string{
 					"X-Custom-Header": "test-value",
@@ -110,9 +110,9 @@ func Test_CreateRequest(t *testing.T) {
 			},
 			expectedURL:    "http://graphite.example.com/metrics/expand",
 			expectedMethod: "POST",
-			checkQuery: map[string]string{
-				"groupByExpr": "true",
-				"leavesOnly":  "false",
+			checkQuery: map[string][]string{
+				"groupByExpr": {"true"},
+				"leavesOnly":  {"false"},
 			},
 			checkHeaders: map[string]string{
 				"X-Custom-Header": "test-value",
@@ -130,16 +130,30 @@ func Test_CreateRequest(t *testing.T) {
 			name:   "empty query parameter values",
 			dsInfo: dsInfo,
 			params: URLParams{
-				QueryParams: map[string]string{
-					"empty": "",
-					"valid": "value",
+				QueryParams: map[string][]string{
+					"empty": {""},
+					"valid": {"value"},
 				},
 			},
 			expectedURL:    "http://graphite.example.com",
 			expectedMethod: "GET",
-			checkQuery: map[string]string{
-				"empty": "",
-				"valid": "value",
+			checkQuery: map[string][]string{
+				"empty": {""},
+				"valid": {"value"},
+			},
+		},
+		{
+			name:   "multi-valued query parameter",
+			dsInfo: dsInfo,
+			params: URLParams{
+				QueryParams: map[string][]string{
+					"valid": {"value1", "value2"},
+				},
+			},
+			expectedURL:    "http://graphite.example.com",
+			expectedMethod: "GET",
+			checkQuery: map[string][]string{
+				"valid": {"value1", "value2"},
 			},
 		},
 	}
@@ -163,9 +177,13 @@ func Test_CreateRequest(t *testing.T) {
 			assert.Equal(t, tt.expectedMethod, req.Method)
 
 			if tt.checkQuery != nil {
-				for key, expectedValue := range tt.checkQuery {
-					actualValue := req.URL.Query().Get(key)
-					assert.Equal(t, expectedValue, actualValue, "Query parameter %s", key)
+				for key, expectedValues := range tt.checkQuery {
+					actualValue := req.URL.Query()[key]
+					assert.NotZero(t, len(actualValue))
+
+					for _, expectedValue := range expectedValues {
+						assert.Contains(t, actualValue, expectedValue, "Query parameter %s", key)
+					}
 				}
 			}
 
diff --git a/pkg/tsdb/graphite/resource_handler.go b/pkg/tsdb/graphite/resource_handler.go
index d8a1c3508ec..dfd1a3c6568 100644
--- a/pkg/tsdb/graphite/resource_handler.go
+++ b/pkg/tsdb/graphite/resource_handler.go
@@ -26,6 +26,8 @@ func (s *Service) newResourceMux() *http.ServeMux {
 	mux.HandleFunc("/metrics/expand", handleResourceReq(s.handleMetricsExpand, s))
 	mux.HandleFunc("/functions", handleResourceReq(s.handleFunctions, s))
 	mux.HandleFunc("/tags/autoComplete/tags", handleResourceReq(s.handleTagsAutocomplete, s))
+	mux.HandleFunc("/tags/autoComplete/values", handleResourceReq(s.handleTagValuesAutocomplete, s))
+
 	return mux
 }
 
@@ -87,12 +89,12 @@ func handleResourceReq[T any](handlerFn resourceHandler[T], s *Service) func(rw
 }
 
 func (s *Service) handleEvents(ctx context.Context, dsInfo *datasourceInfo, eventsRequestJson *GraphiteEventsRequest) ([]byte, int, error) {
-	queryParams := map[string]string{
-		"from":  eventsRequestJson.From,
-		"until": eventsRequestJson.Until,
+	queryParams := map[string][]string{
+		"from":  {eventsRequestJson.From},
+		"until": {eventsRequestJson.Until},
 	}
 	if eventsRequestJson.Tags != "" {
-		queryParams["tags"] = eventsRequestJson.Tags
+		queryParams["tags"] = []string{eventsRequestJson.Tags}
 	}
 
 	req, err := s.createRequest(ctx, dsInfo, URLParams{
@@ -128,12 +130,12 @@ func (s *Service) handleMetricsFind(ctx context.Context, dsInfo *datasourceInfo,
 	data := url.Values{}
 	data.Set("query", metricsFindRequestJson.Query)
 
-	queryParams := map[string]string{}
+	queryParams := map[string][]string{}
 	if metricsFindRequestJson.From != "" {
-		queryParams["from"] = metricsFindRequestJson.From
+		queryParams["from"] = []string{metricsFindRequestJson.From}
 	}
 	if metricsFindRequestJson.Until != "" {
-		queryParams["until"] = metricsFindRequestJson.Until
+		queryParams["until"] = []string{metricsFindRequestJson.Until}
 	}
 
 	req, err := s.createRequest(ctx, dsInfo, URLParams{
@@ -165,14 +167,14 @@ func (s *Service) handleMetricsExpand(ctx context.Context, dsInfo *datasourceInf
 		return nil, http.StatusBadRequest, fmt.Errorf("query is required")
 	}
 
-	queryParams := map[string]string{
-		"query": metricsExpandRequestJson.Query,
+	queryParams := map[string][]string{
+		"query": {metricsExpandRequestJson.Query},
 	}
 	if metricsExpandRequestJson.From != "" {
-		queryParams["from"] = metricsExpandRequestJson.From
+		queryParams["from"] = []string{metricsExpandRequestJson.From}
 	}
 	if metricsExpandRequestJson.Until != "" {
-		queryParams["until"] = metricsExpandRequestJson.Until
+		queryParams["until"] = []string{metricsExpandRequestJson.Until}
 	}
 
 	req, err := s.createRequest(ctx, dsInfo, URLParams{
@@ -205,11 +207,11 @@ func (s *Service) handleMetricsExpand(ctx context.Context, dsInfo *datasourceInf
 }
 
 func (s *Service) handleTagsAutocomplete(ctx context.Context, dsInfo *datasourceInfo, tagsAutocompleteRequestJson *GraphiteTagsRequest) ([]byte, int, error) {
-	queryParams := map[string]string{
-		"from":      tagsAutocompleteRequestJson.From,
-		"until":     tagsAutocompleteRequestJson.Until,
-		"limit":     fmt.Sprintf("%d", tagsAutocompleteRequestJson.Limit),
-		"tagPrefix": tagsAutocompleteRequestJson.TagPrefix,
+	queryParams := map[string][]string{
+		"from":      {tagsAutocompleteRequestJson.From},
+		"until":     {tagsAutocompleteRequestJson.Until},
+		"limit":     {fmt.Sprintf("%d", tagsAutocompleteRequestJson.Limit)},
+		"tagPrefix": {tagsAutocompleteRequestJson.TagPrefix},
 	}
 	req, err := s.createRequest(ctx, dsInfo, URLParams{
 		SubPath:     "tags/autoComplete/tags",
@@ -217,7 +219,7 @@ func (s *Service) handleTagsAutocomplete(ctx context.Context, dsInfo *datasource
 		QueryParams: queryParams,
 	})
 	if err != nil {
-		return nil, http.StatusInternalServerError, fmt.Errorf("failed to create metrics expand request %v", err)
+		return nil, http.StatusInternalServerError, fmt.Errorf("failed to create tags autocomplete request %v", err)
 	}
 
 	tags, _, statusCode, err := doGraphiteRequest[[]string](ctx, dsInfo, s.logger, req, false)
@@ -233,6 +235,38 @@ func (s *Service) handleTagsAutocomplete(ctx context.Context, dsInfo *datasource
 	return tagsResponse, statusCode, nil
 }
 
+func (s *Service) handleTagValuesAutocomplete(ctx context.Context, dsInfo *datasourceInfo, tagValuesAutocompleteRequestJson *GraphiteTagValuesRequest) ([]byte, int, error) {
+	queryParams := map[string][]string{
+		"expr":        tagValuesAutocompleteRequestJson.Expr,
+		"tag":         {tagValuesAutocompleteRequestJson.Tag},
+		"from":        {tagValuesAutocompleteRequestJson.From},
+		"until":       {tagValuesAutocompleteRequestJson.Until},
+		"limit":       {fmt.Sprintf("%d", tagValuesAutocompleteRequestJson.Limit)},
+		"valuePrefix": {tagValuesAutocompleteRequestJson.ValuePrefix},
+	}
+
+	req, err := s.createRequest(ctx, dsInfo, URLParams{
+		SubPath:     "tags/autoComplete/values",
+		Method:      http.MethodGet,
+		QueryParams: queryParams,
+	})
+	if err != nil {
+		return nil, http.StatusInternalServerError, fmt.Errorf("failed to create tag values autocomplete request %v", err)
+	}
+
+	tagValues, _, statusCode, err := doGraphiteRequest[[]string](ctx, dsInfo, s.logger, req, false)
+	if err != nil {
+		return nil, statusCode, fmt.Errorf("tag values autocomplete request failed: %v", err)
+	}
+
+	tagValuesResponse, err := json.Marshal(tagValues)
+	if err != nil {
+		return nil, http.StatusInternalServerError, fmt.Errorf("failed to marshal tag values autocomplete response: %s", err)
+	}
+
+	return tagValuesResponse, statusCode, nil
+}
+
 func (s *Service) handleFunctions(ctx context.Context, dsInfo *datasourceInfo, _ *any) ([]byte, int, error) {
 	req, err := s.createRequest(ctx, dsInfo, URLParams{
 		SubPath: "functions",
diff --git a/pkg/tsdb/graphite/resource_handler_test.go b/pkg/tsdb/graphite/resource_handler_test.go
index c331c2d2cab..c4ba2e201d2 100644
--- a/pkg/tsdb/graphite/resource_handler_test.go
+++ b/pkg/tsdb/graphite/resource_handler_test.go
@@ -9,6 +9,7 @@ import (
 	"io"
 	"net/http"
 	"net/http/httptest"
+	"net/url"
 	"testing"
 
 	"github.com/grafana/grafana-plugin-sdk-go/backend"
@@ -498,6 +499,127 @@ func TestHandleTagsAutocomplete(t *testing.T) {
 		})
 	}
 }
+
+func TestHandleTagValuesAutocomplete(t *testing.T) {
+	tests := []struct {
+		name          string
+		request       GraphiteTagValuesRequest
+		responseBody  string
+		statusCode    int
+		expectError   bool
+		errorContains string
+		expectedData  []string
+	}{
+		{
+			name: "successful tag values autocomplete request",
+			request: GraphiteTagValuesRequest{
+				Expr:        []string{"app=*"},
+				Tag:         "environment",
+				From:        "1h",
+				Until:       "now",
+				Limit:       5,
+				ValuePrefix: "prod",
+			},
+			responseBody: `["production", "prod-eu", "prod-us"]`,
+			statusCode:   200,
+			expectedData: []string{"production", "prod-eu", "prod-us"},
+		},
+		{
+			name: "multiple expressions",
+			request: GraphiteTagValuesRequest{
+				Expr:        []string{"app=*", "region=us-*"},
+				Tag:         "environment",
+				From:        "1h",
+				Until:       "now",
+				Limit:       5,
+				ValuePrefix: "prod",
+			},
+			responseBody: `["production", "prod-eu", "prod-us"]`,
+			statusCode:   200,
+			expectedData: []string{"production", "prod-eu", "prod-us"},
+		},
+		{
+			name: "tag values autocomplete with empty response",
+			request: GraphiteTagValuesRequest{
+				Expr:        []string{"app=nonexistent"},
+				Tag:         "environment",
+				ValuePrefix: "staging",
+			},
+			responseBody: `[]`,
+			statusCode:   200,
+			expectedData: []string{},
+		},
+		{
+			name: "tag values autocomplete server error",
+			request: GraphiteTagValuesRequest{
+				Expr: []string{"invalid-expr"},
+				Tag:  "env",
+			},
+			responseBody:  `invalid json response`,
+			statusCode:    400,
+			expectError:   true,
+			errorContains: "tag values autocomplete request failed",
+		},
+	}
+
+	for _, tt := range tests {
+		t.Run(tt.name, func(t *testing.T) {
+			mockTransport := &mockRoundTripper{
+				respBody: []byte(tt.responseBody),
+				status:   tt.statusCode,
+			}
+
+			dsInfo := &datasourceInfo{
+				HTTPClient: &http.Client{Transport: mockTransport},
+				URL:        "http://graphite.example.com",
+			}
+
+			service := &Service{
+				logger: log.NewNullLogger(),
+			}
+
+			result, statusCode, err := service.handleTagValuesAutocomplete(context.Background(), dsInfo, &tt.request)
+
+			if tt.expectError {
+				assert.Error(t, err)
+				if tt.errorContains != "" {
+					assert.Contains(t, err.Error(), tt.errorContains)
+				}
+			} else {
+				assert.NoError(t, err)
+				assert.Equal(t, tt.statusCode, statusCode)
+
+				var tagValues []string
+				err = json.Unmarshal(result, &tagValues)
+				assert.NoError(t, err)
+				assert.Equal(t, tt.expectedData, tagValues)
+			}
+
+			if !tt.expectError {
+				expectedURL := "http://graphite.example.com/tags/autoComplete/values"
+				assert.Contains(t, mockTransport.lastRequest.URL.String(), expectedURL)
+
+				for _, expr := range tt.request.Expr {
+					assert.Contains(t, mockTransport.lastRequest.URL.RawQuery, fmt.Sprintf("expr=%s", url.QueryEscape(expr)))
+				}
+				assert.Contains(t, mockTransport.lastRequest.URL.RawQuery, fmt.Sprintf("tag=%s", tt.request.Tag))
+
+				if tt.request.From != "" {
+					assert.Contains(t, mockTransport.lastRequest.URL.RawQuery, fmt.Sprintf("from=%s", tt.request.From))
+				}
+				if tt.request.Until != "" {
+					assert.Contains(t, mockTransport.lastRequest.URL.RawQuery, fmt.Sprintf("until=%s", tt.request.Until))
+				}
+				if tt.request.Limit != 0 {
+					assert.Contains(t, mockTransport.lastRequest.URL.RawQuery, fmt.Sprintf("limit=%d", tt.request.Limit))
+				}
+				if tt.request.ValuePrefix != "" {
+					assert.Contains(t, mockTransport.lastRequest.URL.RawQuery, fmt.Sprintf("valuePrefix=%s", tt.request.ValuePrefix))
+				}
+			}
+		})
+	}
+}
 func TestHandleFunctions(t *testing.T) {
 	tests := []struct {
 		name          string
diff --git a/pkg/tsdb/graphite/types.go b/pkg/tsdb/graphite/types.go
index 2e427f1d327..04a3c8e812a 100644
--- a/pkg/tsdb/graphite/types.go
+++ b/pkg/tsdb/graphite/types.go
@@ -16,7 +16,7 @@ type URLParams struct {
 	SubPath     string
 	Method      string
 	Body        io.Reader
-	QueryParams map[string]string
+	QueryParams map[string][]string
 	Headers     map[string]string
 }
 
@@ -66,3 +66,12 @@ type GraphiteTagsRequest struct {
 	Limit     int    `json:"limit,omitempty"`
 	TagPrefix string `json:"tagPrefix,omitempty"`
 }
+
+type GraphiteTagValuesRequest struct {
+	Expr        []string `json:"expr"`
+	Tag         string   `json:"tag"`
+	From        string   `json:"from"`
+	Until       string   `json:"until"`
+	Limit       int      `json:"limit,omitempty"`
+	ValuePrefix string   `json:"valuePrefix,omitempty"`
+}
diff --git a/public/app/plugins/datasource/graphite/datasource.ts b/public/app/plugins/datasource/graphite/datasource.ts
index 14b1139f3ad..2c09afd4b83 100644
--- a/public/app/plugins/datasource/graphite/datasource.ts
+++ b/public/app/plugins/datasource/graphite/datasource.ts
@@ -789,71 +789,6 @@ export class GraphiteDatasource
     );
   }
 
-  getTags(optionalOptions: any) {
-    const options = optionalOptions || {};
-    const params: BackendSrvRequest['params'] = {};
-
-    if (options.range) {
-      params.from = this.translateTime(options.range.from, false, options.timezone);
-      params.until = this.translateTime(options.range.to, true, options.timezone);
-    }
-
-    const httpOptions: BackendSrvRequest = {
-      method: 'GET',
-      url: '/tags',
-      // for cancellations
-      requestId: options.requestId,
-      params,
-    };
-
-    return lastValueFrom(
-      this.doGraphiteRequest(httpOptions).pipe(
-        map((results: FetchResponse) => {
-          return _map(results.data, (tag) => {
-            return {
-              text: tag.tag,
-              id: tag.id,
-            };
-          });
-        })
-      )
-    );
-  }
-
-  getTagValues(options: any = {}) {
-    const params: BackendSrvRequest['params'] = {};
-
-    if (options.range) {
-      params.from = this.translateTime(options.range.from, false, options.timezone);
-      params.until = this.translateTime(options.range.to, true, options.timezone);
-    }
-
-    const httpOptions: BackendSrvRequest = {
-      method: 'GET',
-      url: '/tags/' + this.templateSrv.replace(options.key),
-      // for cancellations
-      requestId: options.requestId,
-      params,
-    };
-
-    return lastValueFrom(
-      this.doGraphiteRequest(httpOptions).pipe(
-        map((results: FetchResponse) => {
-          if (results.data && results.data.values) {
-            return _map(results.data.values, (value) => {
-              return {
-                text: value.value,
-                id: value.id,
-              };
-            });
-          } else {
-            return [];
-          }
-        })
-      )
-    );
-  }
-
   async getTagsAutoComplete(expressions: string[], tagPrefix?: string, optionalOptions?: any) {
     const options = optionalOptions || {};
     const params: BackendSrvRequest['params'] = {
@@ -894,7 +829,7 @@ export class GraphiteDatasource
     return lastValueFrom(this.doGraphiteRequest(httpOptions).pipe(mapToTags()));
   }
 
-  getTagValuesAutoComplete(expressions: string[], tag: string, valuePrefix?: string, optionalOptions?: any) {
+  async getTagValuesAutoComplete(expressions: string[], tag: string, valuePrefix?: string, optionalOptions?: any) {
     const options = optionalOptions || {};
     const params: BackendSrvRequest['params'] = {
       expr: _map(expressions, (expression) => this.templateSrv.replace((expression || '').trim())),
@@ -911,6 +846,20 @@ export class GraphiteDatasource
       params.until = this.translateTime(options.range.to, true, options.timezone);
     }
 
+    if (config.featureToggles.graphiteBackendMode) {
+      const tagValues = await this.postResource<string[]>('tags/autoComplete/values', {
+        from: typeof params.from === 'string' ? params.from : `${params.from}`,
+        until: typeof params.until === 'string' ? params.until : `${params.until}`,
+        expr: params.expr,
+        tag: params.tag,
+        valuePrefix,
+        limit: options.limit,
+      });
+      return tagValues.map((tag) => ({
+        text: tag,
+      }));
+    }
+
     const httpOptions: BackendSrvRequest = {
       method: 'GET',
       url: '/tags/autoComplete/values',