diff --git a/public/app/plugins/datasource/cloud-monitoring/components/MetricQueryEditor.test.tsx b/public/app/plugins/datasource/cloud-monitoring/components/MetricQueryEditor.test.tsx
index ad2f975ba20..b3975ad9438 100644
--- a/public/app/plugins/datasource/cloud-monitoring/components/MetricQueryEditor.test.tsx
+++ b/public/app/plugins/datasource/cloud-monitoring/components/MetricQueryEditor.test.tsx
@@ -1,5 +1,7 @@
 import { render, screen, waitFor } from '@testing-library/react';
+import userEvent from '@testing-library/user-event';
 import React from 'react';
+import { openMenu } from 'react-select-event';
 
 import { getDefaultTimeRange } from '@grafana/data';
 
@@ -80,4 +82,33 @@ describe('MetricQueryEditor', () => {
     render(<MetricQueryEditor {...defaultProps} query={query} />);
     await waitFor(() => expect(screen.getByLabelText('Alias by').closest('input')!.value).toEqual('AliasTest'));
   });
+
+  it('runs a timeSeriesList query if there are no filters', async () => {
+    const onRunQuery = jest.fn();
+    const onChange = jest.fn();
+    const query = createMockQuery();
+
+    render(<MetricQueryEditor {...defaultProps} onRunQuery={onRunQuery} onChange={onChange} query={query} />);
+
+    const groupBy = screen.getByLabelText('Group by');
+    openMenu(groupBy);
+    const option = 'metadata.system_labels.cloud_account';
+    await userEvent.click(screen.getByText(option));
+
+    expect(onRunQuery).toHaveBeenCalledTimes(1);
+    expect(onChange).toHaveBeenCalledTimes(1);
+  });
+
+  it('does not run a timeSeriesList query when filter is added', async () => {
+    const onRunQuery = jest.fn();
+    const onChange = jest.fn();
+    const query = createMockQuery();
+
+    render(<MetricQueryEditor {...defaultProps} onRunQuery={onRunQuery} onChange={onChange} query={query} />);
+
+    const addFilter = screen.getByLabelText('Add');
+    await userEvent.click(addFilter);
+    expect(onRunQuery).toHaveBeenCalledTimes(0);
+    expect(onChange).toHaveBeenCalledTimes(1);
+  });
 });
diff --git a/public/app/plugins/datasource/cloud-monitoring/components/MetricQueryEditor.tsx b/public/app/plugins/datasource/cloud-monitoring/components/MetricQueryEditor.tsx
index 432b5429e91..846ee57fb08 100644
--- a/public/app/plugins/datasource/cloud-monitoring/components/MetricQueryEditor.tsx
+++ b/public/app/plugins/datasource/cloud-monitoring/components/MetricQueryEditor.tsx
@@ -50,8 +50,19 @@ function Editor({
 }: React.PropsWithChildren<Props>) {
   const onChangeTimeSeriesList = useCallback(
     (timeSeriesList: TimeSeriesList) => {
+      let filtersComplete = true;
+      if (timeSeriesList?.filters && timeSeriesList.filters.length > 0) {
+        for (const filter of timeSeriesList.filters) {
+          if (filter === '') {
+            filtersComplete = false;
+            break;
+          }
+        }
+      }
       onQueryChange({ ...query, timeSeriesList });
-      onRunQuery();
+      if (filtersComplete) {
+        onRunQuery();
+      }
     },
     [onQueryChange, onRunQuery, query]
   );