diff --git a/e2e/dashboard-new-layouts/dashboards-edit-datasource-variables.spec.ts b/e2e/dashboard-new-layouts/dashboards-edit-datasource-variables.spec.ts
new file mode 100644
index 00000000000..25b8b8608ac
--- /dev/null
+++ b/e2e/dashboard-new-layouts/dashboards-edit-datasource-variables.spec.ts
@@ -0,0 +1,49 @@
+import { e2e } from '../utils';
+
+import { flows, Variable } from './dashboard-edit-flows';
+
+const PAGE_UNDER_TEST = 'kVi2Gex7z/test-variable-output';
+const DASHBOARD_NAME = 'Test variable output';
+
+describe('Dashboard edit - datasource variables', () => {
+  beforeEach(() => {
+    e2e.flows.login(Cypress.env('USERNAME'), Cypress.env('PASSWORD'));
+  });
+
+  it('can add a new datasource variable', () => {
+    e2e.pages.Dashboards.visit();
+
+    e2e.flows.openDashboard({ uid: `${PAGE_UNDER_TEST}?orgId=1` });
+    cy.contains(DASHBOARD_NAME).should('be.visible');
+
+    const dsType = 'cloudwatch';
+
+    const variable: Variable = {
+      type: 'datasource',
+      name: 'VariableUnderTest',
+      label: 'VariableUnderTest',
+      value: `gdev-${dsType}`,
+    };
+
+    // Common steps to add a new variable
+    flows.newEditPaneVariableClick();
+    flows.newEditPanelCommonVariableInputs(variable);
+
+    e2e.pages.Dashboard.Settings.Variables.Edit.DatasourceVariable.datasourceSelect().should('be.visible').click();
+    cy.get(`#combobox-option-${dsType}`).click();
+
+    const regexFilter = 'cloud';
+    e2e.pages.Dashboard.Settings.Variables.Edit.DatasourceVariable.nameFilter().should('be.visible').type(regexFilter);
+
+    // Assert the variable dropdown is visible with correct label
+    e2e.pages.Dashboard.SubMenu.submenuItemLabels(variable.label).should('be.visible').contains(variable.label);
+
+    // Assert the variable values are correctly displayed in the panel
+    e2e.components.Panels.Panel.content()
+      .should('be.visible')
+      .first()
+      .within(() => {
+        cy.get('.markdown-html').should('include.text', `${variable.name}: ${variable.value}`);
+      });
+  });
+});
diff --git a/packages/grafana-e2e-selectors/src/selectors/pages.ts b/packages/grafana-e2e-selectors/src/selectors/pages.ts
index 0beb8916e32..056f3209ccd 100644
--- a/packages/grafana-e2e-selectors/src/selectors/pages.ts
+++ b/packages/grafana-e2e-selectors/src/selectors/pages.ts
@@ -511,6 +511,9 @@ export const versionedPages = {
             datasourceSelect: {
               [MIN_GRAFANA_VERSION]: 'data-testid datasource variable datasource type',
             },
+            nameFilter: {
+              [MIN_GRAFANA_VERSION]: 'data-testid datasource variable datasource name filter',
+            },
           },
           TextBoxVariable: {
             textBoxOptionsQueryInput: {
diff --git a/public/app/features/dashboard-scene/settings/variables/editors/DataSourceVariableEditor.tsx b/public/app/features/dashboard-scene/settings/variables/editors/DataSourceVariableEditor.tsx
index 27971a47b1d..fb040b268aa 100644
--- a/public/app/features/dashboard-scene/settings/variables/editors/DataSourceVariableEditor.tsx
+++ b/public/app/features/dashboard-scene/settings/variables/editors/DataSourceVariableEditor.tsx
@@ -125,6 +125,7 @@ function DataSourceNameFilter({ variable }: { variable: DataSourceVariable }) {
     <Input
       defaultValue={regex}
       onBlur={onBlur}
+      data-testid={selectors.pages.Dashboard.Settings.Variables.Edit.DatasourceVariable.nameFilter}
       placeholder={t('dashboard.edit-pane.variable.datasource-options.name-filter-placeholder', 'Example: /^prod/')}
     />
   );