diff --git a/docs/sources/datasources/google-cloud-monitoring/_index.md b/docs/sources/datasources/google-cloud-monitoring/_index.md
index 27bc7b390cd..d5412c33ef7 100644
--- a/docs/sources/datasources/google-cloud-monitoring/_index.md
+++ b/docs/sources/datasources/google-cloud-monitoring/_index.md
@@ -103,10 +103,11 @@ To configure basic settings for the data source, complete the following steps:
 
 1. Set the data source's basic configuration options:
 
-   | Name        | Description                                                              |
-   | ----------- | ------------------------------------------------------------------------ |
-   | **Name**    | Sets the name you use to refer to the data source in panels and queries. |
-   | **Default** | Sets whether the data source is pre-selected for new panels.             |
+   | Name                | Description                                                                                                                                                                                                                                                                                                                                                                                                                       |
+   | ------------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
+   | **Name**            | Sets the name you use to refer to the data source in panels and queries.                                                                                                                                                                                                                                                                                                                                                          |
+   | **Default**         | Sets whether the data source is pre-selected for new panels.                                                                                                                                                                                                                                                                                                                                                                      |
+   | **Universe Domain** | The universe domain to connect to. For more information, refer to [Documentation on universe domains](https://docs.cloud.google.com/python/docs/reference/monitoring/latest/google.cloud.monitoring_v3.services.service_monitoring_service.ServiceMonitoringServiceAsyncClient#google_cloud_monitoring_v3_services_service_monitoring_service_ServiceMonitoringServiceAsyncClient_universe_domain). Defaults to `googleapis.com`. |
 
 ### Provision the data source
 
@@ -129,6 +130,7 @@ datasources:
       clientEmail: stackdriver@myproject.iam.gserviceaccount.com
       authenticationType: jwt
       defaultProject: my-project-name
+      universeDomain: googleapis.com
     secureJsonData:
       privateKey: |
         -----BEGIN PRIVATE KEY-----
@@ -152,6 +154,7 @@ datasources:
       clientEmail: stackdriver@myproject.iam.gserviceaccount.com
       authenticationType: jwt
       defaultProject: my-project-name
+      universeDomain: googleapis.com
       privateKeyPath: /etc/secrets/gce.pem
 ```
 
@@ -166,6 +169,7 @@ datasources:
     access: proxy
     jsonData:
       authenticationType: gce
+      universeDomain: googleapis.com
 ```
 
 ## Import pre-configured dashboards
diff --git a/pkg/tsdb/cloud-monitoring/cloudmonitoring.go b/pkg/tsdb/cloud-monitoring/cloudmonitoring.go
index c88feb30a1a..37401de02c4 100644
--- a/pkg/tsdb/cloud-monitoring/cloudmonitoring.go
+++ b/pkg/tsdb/cloud-monitoring/cloudmonitoring.go
@@ -92,7 +92,7 @@ func (s *Service) CheckHealth(ctx context.Context, req *backend.CheckHealthReque
 		}, nil
 	}
 
-	url := fmt.Sprintf("%v/v3/projects/%v/metricDescriptors", dsInfo.services[cloudMonitor].url, defaultProject)
+	url := fmt.Sprintf("%s/v3/projects/%s/metricDescriptors", dsInfo.services[cloudMonitor].url, defaultProject)
 	request, err := http.NewRequest(http.MethodGet, url, nil)
 	if err != nil {
 		return nil, err
@@ -139,6 +139,7 @@ type datasourceInfo struct {
 	defaultProject              string
 	clientEmail                 string
 	tokenUri                    string
+	universeDomain              string
 	services                    map[string]datasourceService
 	privateKey                  string
 	usingImpersonation          bool
@@ -150,6 +151,7 @@ type datasourceJSONData struct {
 	DefaultProject              string `json:"defaultProject"`
 	ClientEmail                 string `json:"clientEmail"`
 	TokenURI                    string `json:"tokenUri"`
+	UniverseDomain              string `json:"universeDomain"`
 	UsingImpersonation          bool   `json:"usingImpersonation"`
 	ServiceAccountToImpersonate string `json:"serviceAccountToImpersonate"`
 }
@@ -179,6 +181,7 @@ func newInstanceSettings(httpClientProvider httpclient.Provider) datasource.Inst
 			defaultProject:              jsonData.DefaultProject,
 			clientEmail:                 jsonData.ClientEmail,
 			tokenUri:                    jsonData.TokenURI,
+			universeDomain:              jsonData.UniverseDomain,
 			usingImpersonation:          jsonData.UsingImpersonation,
 			serviceAccountToImpersonate: jsonData.ServiceAccountToImpersonate,
 			services:                    map[string]datasourceService{},
@@ -194,13 +197,13 @@ func newInstanceSettings(httpClientProvider httpclient.Provider) datasource.Inst
 			return nil, err
 		}
 
-		for name, info := range routes {
+		for name := range routes {
 			client, err := newHTTPClient(dsInfo, opts, &httpClientProvider, name)
 			if err != nil {
 				return nil, err
 			}
 			dsInfo.services[name] = datasourceService{
-				url:    info.url,
+				url:    buildURL(name, dsInfo.universeDomain),
 				client: client,
 			}
 		}
diff --git a/pkg/tsdb/cloud-monitoring/httpclient.go b/pkg/tsdb/cloud-monitoring/httpclient.go
index 5a57e5f4ac8..aa0ed084194 100644
--- a/pkg/tsdb/cloud-monitoring/httpclient.go
+++ b/pkg/tsdb/cloud-monitoring/httpclient.go
@@ -23,12 +23,12 @@ type routeInfo struct {
 var routes = map[string]routeInfo{
 	cloudMonitor: {
 		method: "GET",
-		url:    "https://monitoring.googleapis.com",
+		url:    "https://monitoring.",
 		scopes: []string{cloudMonitorScope},
 	},
 	resourceManager: {
 		method: "GET",
-		url:    "https://cloudresourcemanager.googleapis.com",
+		url:    "https://cloudresourcemanager.",
 		scopes: []string{resourceManagerScope},
 	},
 }
@@ -68,6 +68,13 @@ func getMiddleware(model *datasourceInfo, routePath string) (httpclient.Middlewa
 	return tokenprovider.AuthMiddleware(provider), nil
 }
 
+func buildURL(route string, universeDomain string) string {
+	if universeDomain == "" {
+		universeDomain = "googleapis.com"
+	}
+	return routes[route].url + universeDomain
+}
+
 func newHTTPClient(model *datasourceInfo, opts httpclient.Options, clientProvider *httpclient.Provider, route string) (*http.Client, error) {
 	m, err := getMiddleware(model, route)
 	if err != nil {
diff --git a/pkg/tsdb/cloud-monitoring/resource_handler_test.go b/pkg/tsdb/cloud-monitoring/resource_handler_test.go
index 5f315ef9a59..64742233453 100644
--- a/pkg/tsdb/cloud-monitoring/resource_handler_test.go
+++ b/pkg/tsdb/cloud-monitoring/resource_handler_test.go
@@ -111,7 +111,7 @@ func Test_setRequestVariables(t *testing.T) {
 		im: &fakeInstance{
 			services: map[string]datasourceService{
 				cloudMonitor: {
-					url:    routes[cloudMonitor].url,
+					url:    buildURL(cloudMonitor, "googleapis.com"),
 					client: &http.Client{},
 				},
 			},
diff --git a/public/app/plugins/datasource/cloud-monitoring/components/ConfigEditor/ConfigEditor.tsx b/public/app/plugins/datasource/cloud-monitoring/components/ConfigEditor/ConfigEditor.tsx
index d866ad49185..e3ddd378078 100644
--- a/public/app/plugins/datasource/cloud-monitoring/components/ConfigEditor/ConfigEditor.tsx
+++ b/public/app/plugins/datasource/cloud-monitoring/components/ConfigEditor/ConfigEditor.tsx
@@ -1,10 +1,10 @@
 import { memo } from 'react';
 
-import { DataSourcePluginOptionsEditorProps } from '@grafana/data';
+import { DataSourcePluginOptionsEditorProps, updateDatasourcePluginJsonDataOption } from '@grafana/data';
 import { ConnectionConfig } from '@grafana/google-sdk';
 import { ConfigSection, DataSourceDescription } from '@grafana/plugin-ui';
-import { reportInteraction, config } from '@grafana/runtime';
-import { Divider, SecureSocksProxySettings } from '@grafana/ui';
+import { config, reportInteraction } from '@grafana/runtime';
+import { Divider, Field, Input, SecureSocksProxySettings, Stack } from '@grafana/ui';
 
 import { CloudMonitoringOptions, CloudMonitoringSecureJsonData } from '../../types/types';
 
@@ -36,14 +36,33 @@ export const ConfigEditor = memo(({ options, onOptionsChange }: Props) => {
           <Divider />
           <ConfigSection
             title="Additional settings"
-            description="Additional settings are optional settings that can be configured for more control over your data source. This includes Secure Socks Proxy."
+            description="Additional settings are optional settings that can be configured for more control over your data source. This includes Secure Socks Proxy and Universe Domain."
             isCollapsible
-            isInitiallyOpen={options.jsonData.enableSecureSocksProxy !== undefined}
+            isInitiallyOpen={
+              options.jsonData.enableSecureSocksProxy !== undefined || options.jsonData.universeDomain !== undefined
+            }
           >
-            <SecureSocksProxySettings options={options} onOptionsChange={onOptionsChange} />
+            <Stack direction={'column'}>
+              <Field noMargin label="Universe Domain">
+                <Input
+                  width={50}
+                  value={options.jsonData.universeDomain}
+                  onChange={(event) =>
+                    updateDatasourcePluginJsonDataOption(
+                      { options, onOptionsChange },
+                      'universeDomain',
+                      event.currentTarget.value
+                    )
+                  }
+                  placeholder="googleapis.com"
+                ></Input>
+              </Field>
+              <SecureSocksProxySettings options={options} onOptionsChange={onOptionsChange} />
+            </Stack>
           </ConfigSection>
         </>
       )}
+      <Divider />
     </>
   );
 });
diff --git a/public/app/plugins/datasource/cloud-monitoring/types/types.ts b/public/app/plugins/datasource/cloud-monitoring/types/types.ts
index 849f72ea69b..f2e17444fb0 100644
--- a/public/app/plugins/datasource/cloud-monitoring/types/types.ts
+++ b/public/app/plugins/datasource/cloud-monitoring/types/types.ts
@@ -38,6 +38,7 @@ export interface Aggregation {
 export interface CloudMonitoringOptions extends DataSourceOptions {
   gceDefaultProject?: string;
   enableSecureSocksProxy?: boolean;
+  universeDomain?: string;
 }
 
 export interface CloudMonitoringSecureJsonData extends DataSourceSecureJsonData {}