diff --git a/public/app/features/alerting/unified/Silences.test.tsx b/public/app/features/alerting/unified/Silences.test.tsx
index 0d9d0a44f1d..84c35a27d93 100644
--- a/public/app/features/alerting/unified/Silences.test.tsx
+++ b/public/app/features/alerting/unified/Silences.test.tsx
@@ -12,7 +12,7 @@ import { MatcherOperator } from 'app/plugins/datasource/alertmanager/types';
 import { AccessControlAction } from 'app/types';
 
 import Silences from './Silences';
-import { grantUserPermissions, mockDataSource, MockDataSourceSrv } from './mocks';
+import { grantUserPermissions, MOCK_SILENCE_ID_EXISTING, mockDataSource, MockDataSourceSrv } from './mocks';
 import { AlertmanagerProvider } from './state/AlertmanagerContext';
 import { setupDataSources } from './testSetup/datasources';
 import { DataSourceType } from './utils/datasource';
@@ -51,6 +51,7 @@ const ui = {
   silencedAlertCell: byTestId('alerts'),
   addSilenceButton: byRole('link', { name: /add silence/i }),
   queryBar: byPlaceholderText('Search'),
+  existingSilenceNotFound: byRole('alert', { name: /existing silence .* not found/i }),
   editor: {
     timeRange: byTestId(selectors.components.TimePicker.openButton),
     durationField: byLabelText('Duration'),
@@ -290,6 +291,22 @@ describe('Silence create/edit', () => {
     TEST_TIMEOUT
   );
 
+  it('shows an error when existing silence cannot be found', async () => {
+    renderSilences('/alerting/silence/foo-bar/edit');
+
+    expect(await ui.existingSilenceNotFound.find()).toBeInTheDocument();
+  });
+
+  it('populates form with existing silence information', async () => {
+    renderSilences(`/alerting/silence/${MOCK_SILENCE_ID_EXISTING}/edit`);
+
+    // Await the first value to be populated, after which we can expect that all of the other
+    // existing fields have been filled out as well
+    await waitFor(() => expect(ui.editor.matcherName.get()).toHaveValue('foo'));
+    expect(ui.editor.matcherValue.get()).toHaveValue('bar');
+    expect(ui.editor.comment.get()).toHaveValue('Silence noisy alerts');
+  });
+
   it(
     'silences page should contain alertmanager parameter after creating a silence',
     async () => {
diff --git a/public/app/features/alerting/unified/mocks.ts b/public/app/features/alerting/unified/mocks.ts
index 978cf70a859..7ac3c3dfb13 100644
--- a/public/app/features/alerting/unified/mocks.ts
+++ b/public/app/features/alerting/unified/mocks.ts
@@ -307,10 +307,16 @@ export const mockSilence = (partial: Partial<Silence> = {}): Silence => {
   };
 };
 
+export const MOCK_SILENCE_ID_EXISTING = 'f209e273-0e4e-434f-9f66-e72f092025a2';
+
 export const mockSilences = [
-  mockSilence({ id: '12345' }),
-  mockSilence({ id: '67890', matchers: parseMatchers('foo!=bar'), comment: 'Catch all' }),
-  mockSilence({ id: '1111', status: { state: SilenceState.Expired } }),
+  mockSilence({ id: MOCK_SILENCE_ID_EXISTING }),
+  mockSilence({
+    id: 'ce031625-61c7-47cd-9beb-8760bccf0ed7',
+    matchers: parseMatchers('foo!=bar'),
+    comment: 'Catch all',
+  }),
+  mockSilence({ id: '145884a8-ee20-4864-9f84-661305fb7d82', status: { state: SilenceState.Expired } }),
 ];
 
 export const mockNotifiersState = (partial: Partial<NotifiersState> = {}): NotifiersState => {
diff --git a/public/app/features/alerting/unified/mocks/alertmanagerApi.ts b/public/app/features/alerting/unified/mocks/alertmanagerApi.ts
index b5ad61cc0b1..9c30d8ef699 100644
--- a/public/app/features/alerting/unified/mocks/alertmanagerApi.ts
+++ b/public/app/features/alerting/unified/mocks/alertmanagerApi.ts
@@ -1,7 +1,7 @@
 import { http, HttpResponse } from 'msw';
 import { SetupServer } from 'msw/node';
 
-import { mockAlertmanagerAlert } from 'app/features/alerting/unified/mocks';
+import { MOCK_SILENCE_ID_EXISTING, mockAlertmanagerAlert } from 'app/features/alerting/unified/mocks';
 
 import {
   AlertmanagerChoice,
@@ -51,11 +51,11 @@ export const alertmanagerAlertsListHandler = () =>
     HttpResponse.json([
       mockAlertmanagerAlert({
         labels: { foo: 'bar', buzz: 'bazz' },
-        status: { state: AlertState.Suppressed, silencedBy: ['12345'], inhibitedBy: [] },
+        status: { state: AlertState.Suppressed, silencedBy: [MOCK_SILENCE_ID_EXISTING], inhibitedBy: [] },
       }),
       mockAlertmanagerAlert({
         labels: { foo: 'bar', buzz: 'bazz' },
-        status: { state: AlertState.Suppressed, silencedBy: ['12345'], inhibitedBy: [] },
+        status: { state: AlertState.Suppressed, silencedBy: [MOCK_SILENCE_ID_EXISTING], inhibitedBy: [] },
       }),
     ])
   );
diff --git a/public/app/features/alerting/unified/mocks/server/handlers.ts b/public/app/features/alerting/unified/mocks/server/handlers.ts
index 78bc9baa86c..7fa5949fdc7 100644
--- a/public/app/features/alerting/unified/mocks/server/handlers.ts
+++ b/public/app/features/alerting/unified/mocks/server/handlers.ts
@@ -7,16 +7,23 @@ import {
   alertmanagerChoiceHandler,
 } from 'app/features/alerting/unified/mocks/alertmanagerApi';
 import { datasourceBuildInfoHandler } from 'app/features/alerting/unified/mocks/datasources';
-import { silenceCreateHandler, silencesListHandler } from 'app/features/alerting/unified/mocks/silences';
+import {
+  silenceCreateHandler,
+  silenceGetHandler,
+  silencesListHandler,
+} from 'app/features/alerting/unified/mocks/silences';
 
 /**
  * All mock handlers that are required across Alerting tests
  */
 const allHandlers = [
   alertmanagerChoiceHandler(),
-  silencesListHandler(),
-  silenceCreateHandler(),
   alertmanagerAlertsListHandler(),
+
+  silencesListHandler(),
+  silenceGetHandler(),
+  silenceCreateHandler(),
+
   datasourceBuildInfoHandler(),
 ];
 
diff --git a/public/app/features/alerting/unified/mocks/silences.ts b/public/app/features/alerting/unified/mocks/silences.ts
index e23e6ea9ded..75bf988ed28 100644
--- a/public/app/features/alerting/unified/mocks/silences.ts
+++ b/public/app/features/alerting/unified/mocks/silences.ts
@@ -9,6 +9,17 @@ import { mockSilences } from 'app/features/alerting/unified/mocks';
 export const silencesListHandler = (silences = mockSilences) =>
   http.get('/api/alertmanager/:datasourceUid/api/v2/silences', () => HttpResponse.json(silences));
 
+export const silenceGetHandler = () =>
+  http.get<{ uuid: string }>('/api/alertmanager/:datasourceUid/api/v2/silence/:uuid', ({ params }) => {
+    const { uuid } = params;
+    const matchingMockSilence = mockSilences.find((silence) => silence.id === uuid);
+    if (matchingMockSilence) {
+      return HttpResponse.json(matchingMockSilence);
+    }
+
+    return HttpResponse.json({ message: 'silence not found' }, { status: 404 });
+  });
+
 export const silenceCreateHandler = () =>
   http.post('/api/alertmanager/:datasourceUid/api/v2/silences', () =>
     HttpResponse.json({ silenceId: '4bda5b38-7939-4887-9ec2-16323b8e3b4e' })